
314 Action is a nonprofit political action committee that seeks to elect scientists in the United States.

The AAPI Victory Fund is a Political Action Committee that focuses on mobilizing Asian American and Pacific Islanders (AAPI) eligible voters.

American Bridge 21st Century or AB PAC is a liberal American Super PAC that supports Democratic candidates and opposes Republican candidates. It was founded by David Brock in 2010 and is associated with Media Matters for America. It is an opposition research hub for the Democratic Party. The group physically tracks and monitors Republican candidates and officials and uses social media to deploy its findings.

American Jewish Committee (AJC) is a Jewish advocacy group established on November 11, 1906. It is one of the oldest Jewish advocacy organizations and, according to The New York Times, is "widely regarded as the dean of American Jewish organizations". As of 2009, AJC envisions itself as the "Global Center for Jewish and Israel Advocacy".

The Asian American Action Fund (AAAFund) is an American Democratic political action committee founded in 1999. AAAFund's goal is to increase the voice of Asian Americans and Pacific Islanders (AAPIs) in every level of local, state and federal government in the United States. Specifically, AAAFund addresses the under-representation of AAPIs by organizing campaign volunteers, campaign contributions, technical support, and logistics for both endorsed and un-endorsed candidates running for political office. AAAFund has regional chapters in Northern California, Chicago, Northern Virginia/Maryland/District of Columbia, Southern Ohio, Georgia, and New York City as well as a young professional chapter.

Campaign for Economic Democracy (CED) was a California-based political action committee founded by activist and politician Tom Hayden along with his wife, actress and activist Jane Fonda. The CED was formed to promote New Left issues such as rent control, reduction of water pollution, investing in solar power and fighting against nuclear power, advocating labor rights, women's rights and various anti-war initiatives. The CED helped Hayden shift his radical left image more to the center, to reduce opposition and allow him to win his political campaigns. At the same time, pressure from the CED was intended to move the Democratic Party to the left. The CED successfully passed rent control laws in 1979 in Santa Monica, and they backed the 1986 California Proposition 65 to reduce toxins discharged into public water sources.

The Campaign for Liberty (C4L) is a political organization founded by twelve-term United States Congressman Ron Paul. Campaign for Liberty focuses on educating elected officials and the general public about constitutional issues, and currently provides a membership program. Its legal status is that of a 501(c)(4) nonprofit.

Americans for a Better Tomorrow, Tomorrow was a United States political action committee (PAC) established by Stephen Colbert, who portrayed Dr. Stephen T. Colbert, a mock-conservative political pundit on Comedy Central's satirical television series The Colbert Report. As a super PAC the organization could raise unlimited sums of money from corporations, unions and other groups, as well as wealthy individuals. Speaking in character, Colbert said the money would be raised not only for political ads, but also "normal administrative expenses, including but not limited to, luxury hotel stays, private jet travel, and PAC mementos from Saks Fifth Avenue and Neiman Marcus."

The Committee to Defeat the President was first established as the hybrid Stop Hillary PAC in 2013. The PAC changed its name to the Committee to Defend the President in 2017. Ted Harvey, a former Colorado state senator, chairs the committee.

The Congressional LGBTQ+ Equality Caucus was formed by openly gay representatives Tammy Baldwin and Barney Frank June 4, 2008, to advance LGBT+ rights. The caucus had 165 members in the 116th United States Congress. The caucus is co-chaired by the United States House of Representatives' nine openly LGBTQ members: Representatives David Cicilline, Angie Craig, Sharice Davids, Mondaire Jones, Sean Patrick Maloney, Chris Pappas, Mark Pocan, Mark Takano, and Ritchie Torres.

Correct the Record was a hybrid PAC/super PAC founded by David Brock. It supported Hillary Clinton's 2016 presidential campaign. The PAC aimed to respond to negative online narratives about Clinton.

Democracy for America (DFA) is a progressive political action committee, headquartered in South Burlington, Vermont. Founded by former Democratic National Committee Chair Howard Dean in 2004, DFA leads public awareness campaigns on a variety of public policy issues, trains activists, and provides funding directly to candidates for office. The organization has more than a million members in the United States and internationally.

The Draft Mark Warner for President committee was an effort to promote the candidacy of former Governor of Virginia Mark Warner. It was founded the day after the 2004 presidential election by Democratic Party activist Eddie Ratliff of Virginia. On October 23, 2007, the Draft Warner for President Committee received a letter from the Federal Elections Commission (FEC) in response to the committee's declaration of intent to cease operations, dated October 2, 2007, and was allowed to terminate its affairs and cease filing with the FEC. Warner had announced his intent to become a Senate candidate prior to the committee's letter to the FEC.

EMILY's List is an American political action committee (PAC) that aims to help elect Democratic female candidates in favor of abortion rights to office. It was founded by Ellen Malcolm in 1985.

Empower Texans is a conservative advocacy group in Texas. It is affiliated with Texans for Fiscal Responsibility and the Empower Texans Foundation. Empower Texans is based in Austin with operations in Dallas, Houston, and Midland. Empower Texans focuses on fiscal conservatism by supporting lower taxes and spending restraint. It operates in Republican state-level politics in Texas, targeting candidates whom the group views as insufficiently conservative in Republican primaries.

Forward Together PAC is a leadership political action committee based in Alexandria, Virginia. The Committee's Honorary Chair is current Democratic U.S. Senator and former Governor of Virginia Mark Warner.

The Fraternity and Sorority Political Action Committee is a U.S. political action committee (PAC) which focuses on issues related to freedom of association as it concerns Greek-letter organizations at American colleges and universities. It claims to be the nation's largest PAC "focused solely on higher education issues."

Free the Vote North Carolina is a North Carolina-focused Political Action Committee with the primary goal of lobbying for ballot access reform, to reduce burden on political third parties and unaffiliated candidates. The group seeks to educate North Carolinians about ballot access in their state, and equip voters with the knowledge of where candidates stand on voting right. They also advocate for the reformation of the State's candidate nomination system, and the system of primary elections.

Great America Committee is a political action committee (PAC) registered by Vice President of the United States Mike Pence on May 17, 2017. It is the first example of an active Vice President creating such a type of political action committee while serving in office. Fox News noted Pence's action came only one day after reporting on the Comey memos led to the appointment of a special counsel in the investigation into Russian interference in the 2016 United States elections.

Great America PAC is a Super PAC that supported Donald Trump in the 2016 presidential election. It was founded in 2016 by Eric Beach, a political strategist and veteran of presidential campaigns. Beach soon brought on Ed Rollins, a long time Republican campaign consultant and strategist who served as the campaign manager for Ronald Reagan's 1984 presidential campaign.

The Hillary Victory Fund was a joint fundraising committee for Hillary for America, the Democratic National Committee (DNC), and 33 state Democratic committees. As of May 2016, the Fund had raised $61 million in donations.

Hitting Home PAC was a 527 organization founded by Pete Buttigieg in 2017. Buttigieg launched the PAC in June 2017, several months after his failed bid for the Democratic National Committee chairmanship in its 2017 election.

Hollywood Women's Political Committee was an American political action committee that campaigned for progressive issues. The group was founded by Jane Fonda, Barbra Streisand, and other women in the Greater Los Angeles area. HWPC formed in response to Geraldine Ferraro being selected as the running mate of Walter Mondale to run against President Ronald Reagan in the 1984 United States presidential election. The HWPC helped the Democratic Party wrest majority control in the 1986 U.S. Senate elections, and they helped elect Bill Clinton in the 1992 presidential election. 1992 also saw the HWPC assist in bringing a record number of women into the U.S. Senate, the accomplishment called the Year of the Woman.

Huck PAC is the political action committee of former Arkansas Governor, Mike Huckabee. It was founded in April 2008 by Huckabee, during the 2008 United States Republican presidential primaries. Its mission statement was, "Huck PAC is committed to helping Republicans regain control of the House and Senate, regain a majority of governorships and elect John McCain as the 44th president of the United States." It endorses candidates for various offices, then organizes into local groups in every U.S. county and assists the candidate.

The Independent Citizens Committee of the Arts, Sciences and Professions (ICCASP) (1945–1946) was an American association that lobbied unofficially for New Deal causes, as well as the cause of world peace; members included future US President Ronald Reagan. Some members would later be accused of infiltrating the group to spread socialist, and occasionally pro-Soviet Communist ideas. The group included a chapter sometimes called the "Hollywood Independent Citizens Committee of the Arts, Sciences and Professions" (HICCASP) involved in the Hollywood Ten.

KochPAC is a United States political action committee that represents the interests of Koch Industries and its affiliates.

The LGBTQ Victory Fund, commonly shortened to Victory Fund, is an American political action committee dedicated to increasing the number of openly LGBTQ public officials in the United States. Victory Fund is the largest LGBTQ political action committee in the United States and one of the nation’s largest non-connected PACs.

The Lincoln Project is an American political action committee (PAC) formed in late 2019 by former and incumbent Republicans. During the 2020 presidential election, it aimed to prevent the re-election of Donald Trump and defeat all Republicans in close races running for re-election in the United States Senate. In April 2020, the committee announced its endorsement of Democratic presidential nominee Joe Biden.

Mayday PAC is an American crowd-funded non-partisan Super PAC created by Harvard Law School professor and activist Lawrence Lessig. Its purpose is to help elect candidates to the Congress to pass campaign finance reform. It is notable for raising large sums from numerous contributors in a short span of time – nearly $11 million in 2014 – and was described in the Los Angeles Times as the "super PAC to end all super PACs." The group spent over $10 million in the November 2014 elections, but its strategic plan of electing candidates friendly to campaign finance reform failed.

MeidasTouch is an American political action committee formed in March 2020 with the purpose to stop the reelection of Donald Trump in the 2020 United States presidential election.

The Libertarian Party Mises Caucus (LPMC) is a caucus within the United States Libertarian Party that promotes a more radical version of libertarianism. It was founded in 2017 by Michael Heise, mainly in opposition to Nicholas Sarwark's position as party chairman and the more pragmatic faction of the party. It is named after classical liberal economist Ludwig von Mises

MoveOn is a progressive public policy advocacy group and political action committee. Formed in 1998 around one of the first massively viral email petitions, MoveOn has since grown into one of the largest grassroots progressive campaigning communities in the United States, with a membership of millions.

The National Beer Wholesalers Association (NBWA) is a trade association that represents the interests of more than 2,850 beer distributors throughout the United States before government and the public. In 2020, their political action committee was the second largest, ranked by total amount raised.

The National Committee to Defeat the Mundt Bill AKA "NCDMB" (1948-1950) was an American organization that sought to oppose passage of the Mundt-Nixon Bill and subject of a 15-page report of the House Un-American Activities Committee, two of whose members were US Representatives Karl E. Mundt and Richard M. Nixon.

Onward Together is an American political action organization founded in May 2017 by former U.S. Secretary of State and 2016 Democratic presidential nominee Hillary Clinton to fundraise for progressive political groups including: Swing Left, Indivisible, Color of Change, Emerge America, and Run for Something. Clinton described the group as an effort "to advance the vision that won nearly 66 million votes" of a "fairer, more inclusive, big-hearted America."

Our Revolution is an American progressive political action organization spun out of Senator Bernie Sanders's 2016 presidential campaign to continue its work. The organization's mission is to educate voters about issues, get people involved in the political process, and work to organize and elect progressive candidates. Our Revolution is also the title of a book by Sanders released in November 2016.

"People United Means Action" was a political action committee in the United States that opposed the Democratic Party leadership and the nomination of Senator Barack Obama as the Democratic candidate for President in the 2008 presidential election. PUMA began as an effort by supporters of Obama's primary rival, Senator Hillary Rodham Clinton, who believed that Clinton should have been the Democratic nominee. According to PUMA, "We [were] protesting the 2008 Presidential election because we refuse to support a nominee who was selected by the leadership rather than elected by the voters."

Progress Kentucky is an independent expenditure political action committee (PAC) opposing the re-election of Mitch McConnell. The SuperPAC was formed in December 2012. Progress Kentucky's slogan is a play on Senator Mitch McConnell's 2010 statement setting the Republican Party's agenda for last two years of the first term of President Barack Obama:'"The single most important thing we want to achieve: Electing a new US Senator to represent Kentucky."

The Progressive Democrats of America (PDA) is a progressive political organization and grassroots political action committee operating inside and outside the Democratic Party.

Progressive Majority was an American political action committee that recruited, trained, and campaigned on behalf of progressive politicians for state and local offices. Founded in 2001, the group's stated mission is "to elect progressive champions."

The Public Affairs Council (PAC) is a professional association for people working in public administration and policy. Its mission is to advance the field of public affairs and provide resources to public affairs executives and managers to help them achieve their business and professional goals. Based in Washington, D.C., PAC currently counts over 600 corporations, associations and consulting firms as members.

Randal Howard Paul is an American physician and politician serving as the junior United States Senator from Kentucky since 2011. He is the son of former three-time presidential candidate and twelve-term U.S. Representative of Texas Ron Paul.

Ready PAC, formerly Ready for Hillary, was a super PAC created to draft Hillary Clinton for the 2016 U.S. presidential election. Ready for Hillary focused on grassroots organizing and did not engage in television advertising. The PAC was founded by Adam Parkhomenko and Allida Black.

The Republican Jewish Coalition (RJC), formerly the National Jewish Coalition, founded in 1985, is a 501(c)(4) political lobbying group in the United States that promotes Jewish Republicans. The organization has more than 47 chapters throughout the United States.

Run for Something is a progressive American political organization dedicated to recruiting and supporting young candidates running for down-ballot office. Its mission is to get young progressive candidates from non-traditional backgrounds to run for and win state and local offices, and create a next generation slate of political candidates that will seek higher office in the future.

The Southern Conference for Human Welfare (SCHW) (1938-1948) was an organization that sought to promote New Deal-type reforms to the South in terms of social justice, civil rights, and electoral reform. It folded due to funding problems and allegations of Communist sympathies; its successor was the former sub-group the Education Fund.

Swing Left is a progressive political group in the United States that was created following the election of Donald Trump in 2016. The group was founded to create an easier way for Democrats to volunteer in their nearest swing district. Its initial mission was to win a Democratic majority in the House of Representatives in 2018 by building a network of volunteers and donors in targeted swing districts across the U.S.

The United States India Political Action Committee is a political action committee based in Washington, D.C. Since its founding in 2002 by businessman Sanjay Puri, USINPAC has described its goal as "working closely with other Indian-American organizations to promote fair and balanced policies, and create a platform to enable the entry of Indian Americans in the political process." Particular issues of note have related to legal immigration, counter-terrorism, business relations, global health, religious freedom, education, and US-India trade. USINPAC has also donated significant funding to the political campaigns of both Democratic and Republican politicians, and past Senate candidates supported by USINPAC include Aruna Miller, Aneesh Chopra, Vivek Kundra, and Kesha Ram among others. USINPAC is involved with the annual US business delegation to India, and has periodically held briefings for members of the United States Congress and the United States House of Representatives. An active proponent of the H-1B Visa Program between 2003 and 2008, USINPAC has also supported the U.S.-India Civil Nuclear Agreement, the Hyde Act, the Section 123 Agreement, the Domestic Prosperity and Global Freedom Act, and hate-crime expansions to the Local Law Enforcement Enhancement Act (LLEEA), among others.

VoteVets.org is a political action committee (PAC) and 501(c)(4) nonprofit organization in the United States. It was co-founded in 2006 by Jon Soltz and Jeremy Broussard.

With Honor Fund is an American independent expenditure-only committee registered with the Federal Election Commission, led by military veterans and focused on electing next-generation military veterans to create a more effective government.

Wolf-PAC is an American nonpartisan political action committee formed in 2011 with the goal of adding an "amendment to the United States Constitution to ensure balance, integrity, and transparency to our national system of campaign finance".

The Worldwide LaRouche Youth Movement and the LaRouche Political Action Committee are part of the political organization of controversial American political figure Lyndon LaRouche. The LYM's "war room" is in Leesburg, Virginia, also the headquarters of LPAC. The LaRouche Youth Movement describes itself as an international political movement of young adults, led by Lyndon LaRouche, who promote the revival of classical humanist thought, organize politically to establish a new world economic system based on the power of human creativity to increase the power of the human individual in relation to the universe, and fight for a physical economy which can promote the general welfare of humanity, to develop and move towards better living conditions.