
Bajo Cauca Antioquia is a subregion in the Colombian Department of Antioquia. The region is made up by 6 municipalities. The region cover most of the lower valley of the Cauca River with the department of Antioquia.

Eastern Antioquia is subregion of the Colombian Department of Antioquia. The region consists of 23 municipalities.

Magdalena Medio Antioquia is a subregion in the Colombian Department of Antioquia. The region is made up by 6 municipalities. The region is determined by its location within the Middle Magdalena Region which covers the central area of the Magdalena River basin.

Northeastern Antioquia is a subregion in the Colombian Department of Antioquia. The region is made up by 10 municipalities.

Northern Antioquia is a subregion in the Colombian Department of Antioquia. The region is made up of 17 municipalities.

Southwestern Antioquia is a subregion in the Colombian Department of Antioquia. The region is made up of 24 municipalities and is part of the Colombian Coffee Region.

The Metropolitan Area of the Aburrá Valley is the second most important and populated metropolitan area in Colombia. The region is made up of ten municipalities, Medellín (Colombia) being the most important and largest the capital city of the Antioquia Department.

Urabá Antioquia is a subregion in the Colombian Department of Antioquia. The region is made up by 11 municipalities. Most of this region northern portion is part of the Colombian Caribbean Region bordering the Caribbean sea.

Western Antioquia is a subregion in the Colombian Department of Antioquia. The region is made up by 18 municipalities.