
The Guadeloupe amazon or Guadeloupe parrot, is a hypothetical extinct species of parrot that is thought to have been endemic to the Lesser Antillean island region of Guadeloupe. Mentioned and described by 17th- and 18th-century writers, it received a scientific name in 1789. It was moved to the genus Amazona in 1905, and is thought to have been related to, or possibly the same as, the extant imperial amazon. A tibiotarsus and an ulna bone from the island of Marie-Galante may belong to the Guadeloupe amazon. In 1905, a species of extinct violet macaw was also claimed to have lived on Guadeloupe, but in 2015, it was suggested to have been based on a description of the Guadeloupe amazon.

Anolis marmoratus, commonly known as the leopard anole, Guadeloupe anole, or Guadeloupean anole, is a species of anole that is endemic to the islands of Guadeloupe, in the Caribbean Lesser Antilles.

Anolis terraealtae, the Les Saines anole or Les Saintes anole, is a species of anole lizard endemic to the Îles des Saintes, islands in Guadeloupe in the Caribbean.

Eleutherodactylus pinchoni is a species of frog in the family Eleutherodactylidae. It is endemic to Guadeloupe and known from the Basse-Terre. Common name Grand Cafe robber frog has been coined for it.

The Guadeloupe ameiva was a species of Teiidae lizards that was endemic to Guadeloupe. It is known from specimens collected by early European explorers. The fossil record shows that it once ranged across Guadeloupe, La Désirade, Marie-Galante, and Îles des Saintes, but in most recent times it was restricted to Grand Ilet, just offshore of Petit-Bourg. It was last recorded in 1914. Its extinction likely occurred when this area was decimated by a hurricane in 1928. The Guadeloupe ameiva was reported as a ground-dwelling lizard. It fed on plants and carrion.

The Guadeloupe raccoon is a common raccoon subspecies endemic to the two main islands of Guadeloupe in the Lesser Antilles.

The Guadeloupe woodpecker is a species of bird in the family Picidae. It is endemic to Guadeloupe.

The Lesser Antillean macaw or Guadeloupe macaw is a hypothetical extinct species of macaw that is thought to have been endemic to the Lesser Antillean island region of Guadeloupe. In spite of the absence of conserved specimens, many details about the Lesser Antillean macaw are known from several contemporary accounts, and the bird is the subject of some illustrations. Austin Hobart Clark described the species on the basis of these accounts in 1905. Due to the lack of physical remains, and the possibility that sightings were of macaws from the South American mainland, doubts have been raised about the existence of this species. A phalanx bone from the island of Marie-Galante confirmed the existence of a similar-sized macaw inhabiting the region prior to the arrival of humans and was correlated with the Lesser Antillean macaw in 2015. Later that year, historical sources distinguishing between the red macaws of Guadeloupe and the scarlet macaw of the mainland were identified, further supporting its validity.