The Lepidoptera of Hispaniola consist of both the butterflies and moths recorded from the island of Hispaniola, comprising the two sovereign nations of Haiti and the Dominican Republic.

Acanthostichus hispaniolicus is an extinct species of ant in the subfamily Dorylinae known from a group of possibly Miocene fossils found on Hispaniola. A. hispaniolicus is the first species of the ant genus Acanthostichus to have been described from fossils found in Dominican amber and is the only species of Acanthostichus found in the West Indies.

Anochetus ambiguus is an extinct species of ant in the subfamily Ponerinae known from two possibly Miocene fossils found on Hispaniola. A. ambiguus is one of eight species in the ant genus Anochetus to have been described from fossils found in Dominican amber and is one of a number of Anochetus species found in the Greater Antillies.

Anochetus conisquamis is an extinct species of ant in the subfamily Ponerinae known from one possibly Miocene fossil found on Hispaniola. A. conisquamis is one of eight species in the ant genus Anochetus to have been described from fossils found in Dominican amber and is one of a number of Anochetus species found in the Greater Antilles.

Anochetus corayi is an extinct species of ant in the subfamily Ponerinae known from one possibly Miocene fossil found on Hispaniola. A. corayi is one of eight species in the ant genus Anochetus to have been described from fossils found in Dominican amber and is one of a number of Anochetus species found in the Greater Antillies.

Anochetus dubius is an extinct species of ant in the subfamily Ponerinae known from two possibly Miocene fossils found on Hispaniola. A. dubius is one of eight species in the ant genus Anochetus to have been described from fossils found in Dominican amber and is one of a number of Anochetus species found in the Greater Antillies.

Anochetus exstinctus is an extinct species of ant in the subfamily Ponerinae known from two possibly Miocene fossils found on Hispaniola. A. exstinctus is one of eight species in the ant genus Anochetus to have been described from fossils found in Dominican amber and is one of a number of Anochetus species found in the Greater Antillies.

Anochetus intermedius is an extinct species of ant in the subfamily Ponerinae known from two possibly Miocene fossils found on Hispaniola. A. intermedius is one of eight species in the ant genus Anochetus to have been described from fossils found in Dominican amber and is one of a number of Anochetus species found in the Greater Antilles.

Anochetus lucidus is an extinct species of ant in the subfamily Ponerinae known from two possibly Miocene fossils found on Hispaniola. A. lucidus is one of eight species in the ant genus Anochetus to have been described from fossils found in Dominican amber and is one of a number of Anochetus species found in the Greater Antillies.

The ecomorph concept is a term first coined by Ernest Edward Williams in 1972 which he defined as a “species with the same structural habitat/niche, similar in morphology and behavior, but not necessarily close phyletically.” Williams first applied this definition to the Greater Antillean anoles upon observing their evolutionary radiation, although it has since been used widely elsewhere.

Aphaenogaster amphioceanica is an extinct species of ant in the subfamily Myrmicinae known from a single possibly Miocene fossil found in amber on Hispaniola. At the time of description A. amphioceanica was one of two Aphaenogaster species known from the Caribbean islands.

The ashy gecko is a species of gecko native to Cuba and Hispaniola. It is a small species, dark in color with many white spots. It is also a good climber. Ashy geckos have been introduced to a few small islands in southernmost Florida, and have established populations there.

Azteca alpha is an extinct species of ant in the subfamily Dolichoderinae known from possibly Miocene fossils found on Hispaniola. A. alpha is one of only two species in the genus Azteca to have been described from fossils, both found in Dominican amber. It is the host for a fossil nematode, and has been preserved with scale insects.
Battus zetides, the zetides swallowtail, is a species of butterfly in the family Papilionidae. It is found in Haiti and the Dominican Republic.
Calisto hysius is a butterfly of the family Nymphalidae. It is endemic to Hispaniola.

Cephalotes alveolatus is an extinct species of ant in the subfamily Myrmicinae known from a single Middle Miocene fossil found in amber on Hispaniola. At the time of description C. alveolatus was one of seven fossil ant species placed in the Cephalotes coffeae clade.

Cephalotes caribicus is an extinct species of ant in the subfamily Myrmicinae known from two Middle Miocene fossils found in amber on Hispaniola. At the time of description C. caribicus was one of nine ant species placed in the Cephalotes pinelii clade.

Cephalotes dieteri is an extinct species of ant in the subfamily Myrmicinae known from two Middle Miocene fossils found in amber on Hispaniola. At the time of description, C. dieteri was one of seven fossil ant species placed in the Cephalotes coffeae clade.

Cephalotes hispaniolicus is an extinct species of ant in the subfamily Myrmicinae known from a single Middle Miocene fossil found in amber on Hispaniola. At the time of description C. hispaniolicus was one of six ant species placed in the Cephalotes multispinosus clade.

Cephalotes jansei is an extinct species of arboreal ant of the genus Cephalotes, originally erroneously called Exocryptocerus jansei by its discoverers, characterized by an odd shaped head and the ability to "parachute" by steering their fall if they drop from a tree. Giving their name also as gliding ants. The species was probably native of Hispaniola, however, lack of more evidence makes this uncertain. Their larger and flatter legs, a trait common with other members of the genus Cephalotes, gave them their gliding abilities.

Electromyrmococcus is an extinct genus of mealybug in the Pseudococcidae subfamily Rhizoecinae. The genus currently contains three species, all from the early Miocene, Burdigalian stage, Dominican amber deposits on the island of Hispaniola.

Enischnomyia is an extinct genus of bat fly in the family Streblidae. At the time of its description the new genus comprised a single species, Enischnomyia stegosoma, known from a single Miocene fossil found on Hispaniola. E. stegosoma was the first fossil steblid bat fly described from a fossil, and the only member of the subfamily Nycterophiliinae described from Hispaniola. The species is host for the plasmodiid Vetufebrus ovatus preserved in its salivary glands and midgut.

Formicodiplogaster is an extinct form genus of nematodes in the family Diplogasteridae which currently includes a single described species Formicodiplogaster myrmenema. The species is known from early Miocene fossils found on Hispaniola. F. myrmenema has been preserved in association with Azteca alpha, one of only two known fossil species in the ant genus Azteca.

The Jamaican monarch is a species of milkweed butterfly in the nymphalid Danainae subfamily. It is found in the Dominican Republic, Haiti, and Jamaica. The Danaus cleophile jamaicensis, or Jamaican butterfly, is generally a darker color and smaller compared to the other species of monarch butterflies.
Leptofoenus pittfieldae is an extinct species of wasp in the family Pteromalidae known from early Miocene Burdigalian stage Dominican amber deposits on the island of Hispaniola. The species is known from a single 8.8 millimetres (0.35 in) male specimen excavated from the La Toca mine group northeast of Santiago de los Caballeros in 2008 and deposited in the Insect Fossil Collection at the University of Kansas Natural History Museum in Lawrence, Kansas, where it was studied and described by Dr. Michael S. Engel. The species name pittfieldae honors Ms. Morgan Pittfield, niece of the specimen donor.

Lutzomyia adiketis is an extinct species of sandfly in the moth fly subfamily Phlebotominae. L. adiketis is a vector of the extinct Paleoleishmania neotropicum and both species are solely known from early Miocene Burdigalian stage Dominican amber deposits on the island of Hispaniola.

Mesembrinella caenozoica is an extinct species of blow fly in the family Mesembrinellidae. The species is solely known from the Middle Miocene Dominican amber deposits on the island of Hispaniola.

Nesagapostemon is an extinct monotypic genus of sweat bee in the Halictidae subfamily Halictinae. At present, it contains the single species Nesagapostemon moronei.

Odontomachus pseudobauri is an extinct species of ant in the subfamily Ponerinae known from one possibly Miocene fossil found on Hispaniola. O. pseudobauri is one of two species in the ant genus Odontomachus to have been described from fossils found in Dominican amber and is one of a number of Odontomachus species found in the Greater Antilles.

Odontomachus spinifer is an extinct species of ant in the subfamily Ponerinae known from one possibly Miocene fossil found on Hispaniola. O. spinifer is one of two species in the ant genus Odontomachus to have been described from fossils found in Dominican amber and is one of a number of Odontomachus species found in the Greater Antilles.

Oligochlora is an extinct genus of sweat bee in the Halictidae subfamily Halictinae. The genus currently contains six species, all of which are known from the early Miocene Burdigalian stage Dominican amber deposits on the island of Hispaniola.

Palaeoplethodon hispaniolae is an extinct salamander species found in Miocene Dominican amber from the Dominican Republic. It is so far the only salamander species known to have existed in the Caribbean.

Papilio aristodemus, the Schaus' swallowtail or island swallowtail, is a species of American butterfly in the family Papilionidae. It is found in southern Florida with subspecies in the Bahamas, Hispaniola, and Cuba. Historically it occurred in tropical hardwood hammock from South Miami to Lower Matecumbe Key, Florida. It is named in honor of William Schaus.

Pseudochrysops is a genus of butterflies in the family Lycaenidae. This genus is monotypic, consisting of only one species, Pseudochrysops bornoi, which is found on Haiti, Puerto Rico and Cuba.

Termitaradus mitnicki is an extinct species of true bug in the family Termitaphididae known only from early Miocene Burdigalian stage Dominican amber deposits on the island of Hispaniola.

Triatoma dominicana is an extinct species of assassin bug in the subfamily Triatominae, the kissing bugs known from early Miocene Burdigalian stage Dominican amber deposits on the island of Hispaniola.