
Afrotyphlops schlegelii, commonly known as Schlegel's beaked blind snake or Schlegel's giant blind snake, is a species of snake in the family Typhlopidae. The species is endemic to eastern and southern Africa, and bears the distinction of being the world's largest typhlopid. It is harmless to humans and lives exclusively on a diet of termites.

The berg adder is a small, venomous viper species endemic to mountainous regions in southern Africa. No subspecies are currently recognized.

Chondrodactylus bibronii, commonly known as Bibron's thick-toed gecko, Bibron's sand gecko, or simply Bibron's gecko, is a species of lizard in the family Gekkonidae. The species is native to southern Africa. C. bibronii has been used as an animal model in bioastronautic research examining the effects of spaceflight on the morphology and physiology of vertebrates.

Boaedon capensis, the Cape house snake, also known as the brown house snake, is a species of lamprophiid from Botswana, South Africa, Mozambique, Zambia and Zimbabwe. They are a non-venomous lamprophiid. This species was previously grouped in the genus Lamprophis but is regrouped with the genus Boaedon.

The Cape grass lizard, also known as the Cape snake lizard or the highland grass lizard, is a species of lizard in the genus Chamaesaura. It widely found in southern Africa, inhabiting grasslands. In one of the countries it lives in, Swaziland, it is listed as a Near Threatened species.

The common flat lizard is a species of lizard in the Cordylidae family. This lizard has 9 subspecies, all living in southern Africa.

Crotaphopeltis hotamboeia, commonly known as the herald snake or the red-lipped snake, is a species of snake in the family Colubridae. The species is endemic to Sub-Saharan Africa.

Dipsadoboa aulica, commonly known as the marbled tree snake, is a species of snake in the family Colubridae. The species is endemic to Africa, and is mildly venomous to humans.
The East African spiny-tailed lizard, also commonly known as the dwarf sungazer or the tropical girdled lizard, is a species of arboreal or rupicolous (rock-dwelling) lizard endemic to East Africa.

Elasmodactylus tetensis, commonly known as the Tete thick-toed gecko or Zambezi thick-toed gecko, is a species of gecko endemic to East Africa.

The emperor flat lizard or imperial flat lizard is a species of lizard in the Cordylidae family.

Heliobolus lugubris, also known commonly as the bushveld lizard, mourning racerunner, or the black and yellow sand lizard, is a species of lizard in the family Lacertidae. The species is native to southern Africa.

Hemidactylus platycephalus, also known as the tree gecko, flathead leaf-toed gecko, or Baobab gecko, is a species of gecko. It is widely distributed in eastern Africa between Somalia in the north and Mozambique and Madagascar in the south.

Ichnotropis capensis is a species of African lizard, which is native to the southern Afrotropics. It is the type species for the genus Ichnotropis, and is commonly called the Cape rough-scaled lizard due to them being found in southern Africa's Cape region. They are also called ornate rough-scaled lizard or Smith's rough-scaled sand lizard. The small lizards are terrestrial and occur in grassland, desert and brush areas of southern Africa.

Marshall's pygmy chameleon, also called Marshall's leaf chameleon or Marshall's dwarf chameleon, is a species of chameleon found in the forests of Zimbabwe and Mozambique in Africa. It grows from 3.5 to 7.5 cm and feeds on insects. When standing still, it resembles a leaf on a branch.

Trioceros melleri, with the common names Meller's chameleon and giant one-horned chameleon, is the largest species of chameleon from the African mainland.
The Mozambique girdled lizard or flame-bellied armadillo lizard is a large, flattened, girdled lizard found on Mount Gorongosa in Mozambique and low elevations in the Chimanimani Mountains at the border of Zimbabwe and Mozambique. It lives in rock outcrops in grasslands and dry, wooded mountain slopes.

The Natal hinge-back tortoise, also known as Natal hinge-backed tortoise or Natal hinged tortoise, is a species of tortoise in the family Testudinidae which is restricted to eastern southern Africa to a relatively small area around the borders of Mozambique, South Africa, and Eswatini.

The Okavango dwarf gecko or Chobe dwarf gecko is a species of gecko found along the Chobe and Zambesi Rivers and into the Okavango Delta, and into Mozambique, Zimbabwe and Zambia.

Pachydactylus punctatus, also known as the pointed thick-toed gecko or speckled thick-toed gecko, is a species of lizard in the family Gekkonidae. It is found in southern Africa.

Pachydactylus vansoni, commonly known as Van Son's gecko or Van Son's thick-toed gecko, is a species of lizard in the family Gekkonidae. The species is endemic to Southern Africa.

Peters's threadsnake is a species of snake in the family Leptotyphlopidae. It widely distributed in Eastern and Southern Africa, from southern Tanzania south to Natal and west to Angola and Namibia. Leptotyphlops pitmani and Leptotyphlops merkeri were formerly considered subspecies of this species but have now been elevated to full species status.

Philothamnus natalensis, commonly known as the Natal green snake, is a species of snakes in the family Colubridae. The species is found in South Africa, Eswatini, Mozambique and Zimbabwe. Philothamnus occidentalis was previously considered a subspecies.

Psammophis angolensis, sometimes known as the dwarf sand snake, is a species of snake in the family Lamprophiidae reaching a maximum length of 50 cm, but averaging 30 cm. The snake actively forages for lizards and frogs.

The Pungwe flat lizard is a species of lizard in the Cordylidae family.

Telescopus semiannulatus, commonly known as the common tiger snake, tiger cat snake, or western tiger snake is a species of rear-fanged colubrid snake. It is widespread in central, eastern, and southern Africa.

Trachylepis comorensis is a species of skink. It is found in the Comoro Islands, Madagascar and Mozambique.

Trachylepis lacertiformis, the bronze rock skink, is a species of skink found in Zimbabwe, Angola, Malawi, and Mozambique.

Trachylepis wahlbergii, also known commonly as Wahlberg's striped skink, is a species of lizard in the family Scincidae. The species is native to Southern Africa.

The Transvaal rock gecko is a species of gecko endemic to Southern Africa.

The white-headed dwarf gecko or painted dwarf gecko is a species of Lygodactylus gecko widely distributed in Africa.