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Agathotoma finalis is a species of sea snail, a marine gastropod mollusk in the family Mangeliidae. It was first described in 1992.

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Agathotoma merlini is a species of sea snail, a marine gastropod mollusk in the family Mangeliidae. First described in 1910, its species name refers to Martial Henri Merlin, governor-general of French Congo. It occurs on the coast of Africa, and also on the islands of São Tomé and Príncipe.

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Archachatina bicarinata is a species of air-breathing tropical land snail, a terrestrial pulmonate gastropod mollusk in the family Achatinidae.

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Bursa rhodostoma, common name the wine-mouth frog shell, is a species of sea snail, a marine gastropod mollusk in the family Bursidae, the frog shells.

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Charaxes odysseus is a butterfly in the family Nymphalidae. It is found on the island of São Tomé. The species was described by Otto Staudinger in 1892.

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Charaxes thomasius is a butterfly in the family Nymphalidae. It is found on the island of São Tomé.

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Clanculus spadiceus is a species of sea snail, a marine gastropod mollusk in the family Trochidae, the top snails.

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Clavatula muricata, common name the muricate turrid, is a species of sea snail, a marine gastropod mollusk in the family Clavatulidae.

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Crassispira sacerdotalis is a species of small predatory sea snail, a marine gastropod mollusk in the family Pseudomelatomidae, the turrids and allies.

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Drillia idalinae is a species of sea snail, a marine gastropod mollusk in the family Drilliidae.

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Granulina parilis is a species of minute sea snail, a marine gastropod mollusk in the family Granulinidae.

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Haedropleura ryalli is a species of sea snail, a marine gastropod mollusk in the family Horaiclavidae.

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Haliotis geigeri is a species of sea snail, a marine gastropod mollusc in the family Haliotidae, the abalones.

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Haliotis marmorata is a species of sea snail, a marine gastropod mollusk in the family Haliotidae, the abalones.

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Isara gabonensis is a species of sea snail, a marine gastropod mollusk in the family Mitridae, the miters or miter snails.

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Marginella britoi is a species of sea snail, a marine gastropod mollusc in the family Marginellidae, the marginellids.

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Marginella chalmersi is a species of colorful small sea snail, a marine gastropod mollusk in the Marginellidae family. This species is endemic to São Tomé and Príncipe.

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Marginella gemma is a species of small colorful sea snail, a marine gastropod mollusk in the family Marginellidae.

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Marginella hernandezi is a species of sea snail, a marine gastropod mollusc in the family Marginellidae, the marginellids.

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Marginella liparozona is a species of colorful small sea snail, a marine gastropod mollusk in the Marginellidae family.

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Marginella melvilli is a species of colorful small sea snail, a marine gastropod mollusk in the family Marginellidae.

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Marginella spinacia is a species of sea snail, a marine gastropod mollusk in the family Marginellidae, the margin snails.

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Mitromorpha suarezi is a species of sea snail, a marine gastropod mollusk in the family Mitromorphidae.

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Muricopsis delemarrei is a species of sea snail, a marine gastropod mollusk in the family Muricidae, the murex snails or rock snails.

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Muricopsis gorii is a species of small sea snail, a marine gastropod mollusks in the family Muricidae, the rock snails.

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Muricopsis matildeae is a species of small sea snail, a marine gastropod mollusk in the family Muricidae, the rock snails.

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Muricopsis rutila, common name : the beaded drupe, is a species of sea snail, a marine gastropod mollusk in the family Muricidae, the murex snails or rock snails.

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Neritilia manoeli is a species of minute freshwater snail with an operculum, an aquatic gastropod mollusk or micromollusk in the family Neritiliidae.

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Pyramidella dolabrata, common name the "giant Atlantic pyram", is a somewhat variable species of small to medium-sized sea snail, a marine gastropod mollusk in the family Pyramidellidae, the pyram snails.

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Scaevatula amancioi is a species of sea snail, a marine gastropod mollusk in the family Clavatulidae.

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Thyrophorella thomensis is a species of small air-breathing land snail, a terrestrial pulmonate gastropod mollusk in the family Achatinidae. This species is endemic to São Tomé and Príncipe.