
Acontias orientalis, the Eastern striped blindworm or Eastern Cape legless skink, is a species of lizard in the family Scincidae. It is endemic to South Africa.

The Transvaal rock gecko is a species of gecko endemic to Southern Africa.

Arthroleptella is a genus of frogs known as moss frogs in the family Pyxicephalidae. The ten species of this genus are endemic to South Africa.

Tradouw's mountain toad is a species of toad in the family Bufonidae endemic to South Africa. Its natural habitats are Mediterranean-type shrubby vegetation, temperate grassland, rivers, intermittent rivers, swamps, freshwater marshes, and intermittent freshwater marshes. It is threatened by habitat loss.

The climbing mantella is a species of frog in the family Mantellidae. It is endemic to Madagascar. Its natural habitat is subtropical or tropical moist lowland forests. It is threatened by habitat loss.

Gephyromantis luteus, commonly known as the white Folohy Madagascar frog, is a species of frog in the family Mantellidae. It is endemic to Madagascar. Its natural habitat is subtropical or tropical moist lowland forests. It is threatened by habitat loss.

Gephyromantis malagasius, commonly known as the Malasay grainy frog, is a species of frog in the family Mantellidae. It is endemic to Madagascar. Its natural habitats are subtropical or tropical moist lowland forests and subtropical or tropical moist montane forests. It is threatened by habitat loss.

Goggia essexi, also known as Essex's dwarf leaf-toed gecko or Essex's pygmy gecko is a species of gecko. It is endemic to South Africa.

The Hewitt's red rock hare is a species of mammal in the family Leporidae. It had previously been classified as a subspecies of Pronolagus rupestris, but is now regarded as its own species due to differences in morphology and genetic differences in cytochrome b, and 12S rRNA.

Hyperolius semidiscus is a species of frogs in the family Hyperoliidae. It is found in southern and eastern South Africa and in Eswatini, and it is likely to be present in Mozambique. Common names yellow-striped reed frog, yellow-flanked reed frog, and Hewitt's reed frog have been coined for it.

The climbing mantella is a species of frog in the family Mantellidae. It is endemic to Madagascar. Its natural habitat is subtropical or tropical moist lowland forests. It is threatened by habitat loss.

The micro frog, or Cape Flats frog, is a species of frog less than 2 cm (0.8 in) long in the family Pyxicephalidae, in the monotypic genus Microbatrachella. Its color varies from rufous brown with dark mottling, to tan or green, depending on the population. It is endemic to the south-western Cape area of South Africa, with a single population found on the Cape Flats of Cape Town and several populations on the eastern side of False Bay. It typically lives in wetlands in coastal fynbos habitats, but its total area of occupancy is very small, and the International Union for Conservation of Nature has rated it as being "critically endangered".

The Natal hinge-back tortoise, also known as Natal hinge-backed tortoise or Natal hinged tortoise, is a species of tortoise in the family Testudinidae which is restricted to eastern southern Africa to a relatively small area around the borders of Mozambique, South Africa, and Eswatini.

Natalobatrachus bonebergi, the Natal diving frog, Boneberg's frog, or Kloof frog ), is a species of frog in the family Pyxicephalidae. It is the only species within the monotypic genus Natalobatrachus. It is endemic to South Africa. Its natural habitats are temperate forests and rivers and it is threatened by habitat loss.

Natalobatrachus bonebergi, the Natal diving frog, Boneberg's frog, or Kloof frog ), is a species of frog in the family Pyxicephalidae. It is the only species within the monotypic genus Natalobatrachus. It is endemic to South Africa. Its natural habitats are temperate forests and rivers and it is threatened by habitat loss.

Ninurta coeruleopunctatus, the blue-spotted girdled lizard or simply blue-spotted lizard, is a lizard species endemic to southern, coastal South Africa.
Standing's day gecko is an arboreal and diurnal species of lizard in the family Gekkonidae. The species is endemic to southwest Madagascar; it is threatened by illegal collection for the international pet trade and habitat loss. It is among the largest living species of day geckos. Standing's day gecko feeds on insects and nectar.

The Pondo rock gecko or Pondo flat gecko is a species of African gecko found in South Africa and Swaziland.

Poyntonophrynus fenoulheti is a species of small toad found in southern Africa. It is known under many common names, including Fenoulhet's toad, Fenoulhet's pygmy toad, and northern pygmy toad. It grows to a maximum size of 43 mm.

Bradfield's Namib day gecko is a species of lizard in the family Gekkonidae. The species is endemic to Namibia. This species was first described in 1935 by the British-born, South African zoologist John Hewitt, who gave it the name Rhoptropus bradfieldi in honour of the South African naturalist and collector R.D. Bradfield.

The Rose's ghost frog or Table Mountain ghost frog is a species of frog in the family Heleophrynidae endemic to South Africa. It is a medium-sized species with purple or brown blotches on a pale green background and large discs on its fingers and toes. It has a very restricted range, being only known from the slopes of parts of Table Mountain. The tadpoles live in permanent streams but these are in danger of drying up because of the establishment of pine plantations. Because of its small range and changes in its habitat, this frog is listed as critically endangered by the International Union for Conservation of Nature.

The royal ghost frog, also known as the southern ghost frog or Cape ghost frog, is a species of frog in the family Heleophrynidae. It is endemic to South Africa, and lives in fast-moving streams.

The southern rock lizard is a species of lizard in the family Lacertidae. It is endemic to the Western Cape, South Africa. It occurs in fynbos on the rocky mountain slopes.

Spinomantis aglavei is a species of frog in the mantellid subfamily Mantellinae, endemic to Madagascar.
Standing's day gecko is an arboreal and diurnal species of lizard in the family Gekkonidae. The species is endemic to southwest Madagascar; it is threatened by illegal collection for the international pet trade and habitat loss. It is among the largest living species of day geckos. Standing's day gecko feeds on insects and nectar.

Stevenson's dwarf gecko is a species of lizard in the family Gekkonidae. The species is native to southern Africa.

Tradouw's mountain toad is a species of toad in the family Bufonidae endemic to South Africa. Its natural habitats are Mediterranean-type shrubby vegetation, temperate grassland, rivers, intermittent rivers, swamps, freshwater marshes, and intermittent freshwater marshes. It is threatened by habitat loss.

The Transvaal rock gecko is a species of gecko endemic to Southern Africa.

Tropidosaura gularis, the Cape mountain lizard or yellow-striped mountain lizard, is a species of lizard endemic to South Africa.