
Alexander Outlaw Anderson was an American attorney who represented Tennessee in the United States Senate, and later served in the California State Senate, and on the California Supreme Court.

Lloyd James Austin III is a retired four-star general of the United States Army. He was the 12th commander of United States Central Command (CENTCOM). Austin was the first Black commander to head the organization.

Herbert Leon "Sonny" Callahan is an American businessman and politician from Alabama. After being elected as a Democrat from Mobile to the state house and senate, he shifted to the Republican Party after losing a race for Lieutenant Governor of Alabama in 1982. Callahan was repeatedly elected as a Republican to the United States House of Representatives, serving from 1985 to 2003. Afterward he established his own lobbying firm and continued to be active in the Republican Party.

Lloyd Toulmin Chalker was an American naval officer who served as vice commandant of the United States Coast Guard and is credited as the "father of Coast Guard aviation".

Keith L. Craig is an entertainment executive currently working in Burbank, California, at Walt Disney Studios managing Central Division theatrical sales and distribution for Walt Disney Studios Motion Pictures in 20 theatrical demographic market areas, primarily responsible for ensuring the prompt and timely delivery of film to exhibitors and the accurate execution of administrative and logistical oversight required to do so.

Zachariah Cantey Deas was a prominent Southern United States cotton broker and soldier. He served as a brigadier general in the Confederate States Army during the American Civil War.

Jeremiah Andrew Denton Jr. was a U.S. Senator representing Alabama from 1981 to 1987, a United States Navy Rear Admiral, and Naval Aviator taken captive during the Vietnam War.

William Jackson Edwards was an Alabama lawyer and politician who represented the 1st Congressional district in the United States House of Representatives from 1965 to 1985. A Republican, Edwards first won election to Congress in 1964, one of five Republicans elected to the House from Alabama amid Republican presidential nominee Barry Goldwater's sweep of the state in that year's presidential election.

William Crawford Gorgas KCMG was a United States Army physician and 22nd Surgeon General of the U.S. Army (1914–1918). He is best known for his work in Florida, Havana and at the Panama Canal in abating the transmission of yellow fever and malaria by controlling the mosquitoes that carry these diseases. At the time, his strategy was greeted with considerable skepticism and opposition to such hygiene measures. However, the measures he put into practice as the head of the Panama Canal Zone Sanitation Commission saved thousands of lives and contributed to the success of the Canal's construction.

James Hagan was a United States Army captain during the Mexican–American War and a Confederate States Army colonel during the American Civil War. He was a prosperous businessman and planter at Mobile, Alabama between the wars.

Kathryn Patricia "Kay" Hire is a former NASA astronaut and Captain in the U.S. Navy Reserve who has flown aboard two Space Shuttle missions.
Samuel Leon Jones is an American politician who is a member of the Alabama House of Representatives representing district 99. Jones was the first African-American mayor of Mobile, Alabama, serving from September 2005 until August 2013. He ran on a platform of safety, efficient government, historic preservation and bringing new employers to the city.

Alexander McKinstry was the third Lieutenant Governor of Alabama. A Republican, McKinstry served under Governor David P. Lewis of the same political party from 1872 to 1874. He was the last Republican to serve as Lieutenant Governor until Steve Windom was sworn-in 125 years later.

Antonio Narbona was a Spanish soldier from Mobile, now in Alabama, who fought native American people in the northern part of Mexico around the turn of the nineteenth century. He supported the independence of Mexico from Spain in 1821. He was Governor of the territory of Santa Fe de Nuevo México from September 1825 until 1827.

Private First Class John Dury New was a United States Marine who for his gallantry in action at the cost of his life on Peleliu, posthumously received the Medal of Honor.

John Lawrence Rapier was an American Civil War soldier and businessman. A native of Mobile, Alabama, he saw action as a sergeant major in the Seven Days Battles, and later became a second lieutenant in the Confederate States Marine Corps. He was captured at Fort Gaines, Mobile Bay, Alabama, August 5, 1864, and paroled at Nanna Hubba Bluff, Alabama, May 10, 1865.

Raphael Semmes was an officer in the Confederate Navy during the American Civil War. Until then, he had been a serving officer in the US Navy from 1826 to 1860.

Eugene Bondurant Sledge was a United States Marine, university professor, and author. His 1981 memoir With the Old Breed: At Peleliu and Okinawa chronicled his combat experiences during World War II and was subsequently used as source material for the Ken Burns PBS documentary The War (2007), as well as the HBO miniseries The Pacific (2010), in which he is portrayed by Joseph Mazzello.

Leighton Warren Smith Jr. is a former United States Navy admiral. In 1994, he became the Commander in Chief of United States Naval Forces Europe and Allied Forces Southern Europe, holding the commands during the height of the Yugoslav wars. He commanded the NATO enacted no-fly zone over Bosnia and the later bombing campaign against Republika Srpska in 1995. The same year he additionally took on command of the NATO-led Implementation Force (IFOR) in Bosnia with the objective of overseeing the peace agreement. He held all three positions until his retirement in 1996.

Avelin Paul Tacon Jr. was an American Air Force major general.

Alfred Gustave Ward was an admiral in the United States Navy. From 1965 to 1968, Ward was assigned as U.S. Military Representative, NATO Military Committee. During the Cuban Missile Crisis of 1962, Ward, then commander of the Second Fleet and Strike Fleet, Atlantic, was also responsible for supervising the blockade of Cuba. He died in 1982 at the Perry Point Veterans Administration Medical Center.

Clifton Curtis "C.C." Williams Jr., was an American naval aviator, test pilot, mechanical engineer, major in the United States Marine Corps, and NASA astronaut, who was killed in a plane crash; he never went into space. The crash was caused by a mechanical failure in a NASA T-38 jet trainer, which he was piloting to visit his parents in Mobile, Alabama. The failure caused the flight controls to stop responding, and although he activated the ejection seat, it did not save him. He was the fourth astronaut from NASA's Astronaut Group 3 to have died, the first two having been killed in separate T-38 flights, and the third in the Apollo 1 fire earlier that year. The aircraft crashed in Florida near Tallahassee within an hour of departing Patrick AFB.

Jones Mitchell Withers was a United States Army officer who fought during the Mexican–American War and later served as a Confederate major general during the American Civil War. He also was a lawyer, politician, and businessman from the state of Alabama.