
James Addison Baker III is an American attorney and political figure. He served as White House Chief of Staff and United States Secretary of the Treasury under President Ronald Reagan, and as U.S. Secretary of State and White House Chief of Staff under President George H. W. Bush.

Howard Malcolm "Mac" Baldrige Jr. was an American businessman. He served as the United States Secretary of Commerce from 1981 until his death in 1987. He was inducted into the ProRodeo Hall of Fame in 1988.

Terrel Howard Bell was the Secretary of Education in the Cabinet of President Ronald Reagan. He was the second Secretary of Education, following Shirley Hufstedler.

William John Bennett is an American conservative pundit, politician, and political theorist, who served as Secretary of Education from 1985 to 1988 under President Ronald Reagan. He also held the post of Director of the Office of National Drug Control Policy under George H. W. Bush.

John Rusling Block is a former U.S. Secretary of Agriculture, during the Reagan administration. He later became a lobbyist.

Otis Ray Bowen was an American politician and physician who served as the 44th Governor of Indiana from 1973 to 1981 and as Secretary of Health and Human Services from 1985 to 1989.

Nicholas Frederick Brady is an American politician from the state of New Jersey, who was the United States Secretary of the Treasury under Presidents Ronald Reagan and George H. W. Bush, and is also known for articulating the Brady Plan in March 1989. In 1982, he was appointed to succeed Harrison A. Williams as a United States Senator until a special election could be held. He served in the Senate for 8 months.

William Emerson Brock III is a former American Republican politician who served in both chambers of the United States Congress from 1963 to 1977 and later in the United States Cabinet from 1981 to 1987. He is the grandson of William Emerson Brock Sr., a Democratic U.S. senator who represented Tennessee from 1929 to 1931.

James Horace Burnley IV is an American politician and lawyer. He served as the United States Secretary of Transportation from 1987 until 1989, during the administration of President Ronald Reagan. He is a partner at Venable LLP in Washington, D.C.

George Herbert Walker Bush was an American politician, diplomat, and businessman who served as the 41st president of the United States from 1989 to 1993. A member of the Republican Party, Bush also served as the 43rd vice president from 1981 to 1989, in the U.S. House of Representatives, as U.S. Ambassador to the United Nations, and as Director of Central Intelligence.
Frank Charles Carlucci III was an American politician and diplomat who served as the United States Secretary of Defense from 1987 to 1989 in the administration of President Ronald Reagan.

William Joseph Casey was the Director of Central Intelligence from 1981 to 1987. In this capacity he oversaw the entire United States Intelligence Community and personally directed the Central Intelligence Agency (CIA).

Lauro Fred Cavazos Jr. is an American educator and politician. He served as the United States Secretary of Education, and was the first Hispanic to serve in the United States Cabinet.

William Patrick Clark Jr. was an American rancher, judge, and public servant who served under President Ronald Reagan as the Deputy Secretary of State from 1981 to 1982, United States National Security Advisor from 1982 to 1983, and the Secretary of the Interior from 1983 to 1985.

Mary Elizabeth "Liddy" Alexander Hanford Dole is an American politician and author who served in the Richard Nixon, Ronald Reagan, and George H. W. Bush presidential administrations. She also served in the United States Senate from 2003 to 2009.

Raymond James Donovan is an American businessman and former politician. He served as U.S. Secretary of Labor under President Reagan.

James Burrows Edwards was an American politician and administrator from South Carolina. He was the first Republican to be elected governor of South Carolina since the post-Civil War Reconstruction Era in the 1870s. He later served as the U.S. Secretary of Energy under Ronald Reagan.

Alexander Meigs Haig Jr. was the United States Secretary of State under President Ronald Reagan and the White House chief of staff under presidents Richard Nixon and Gerald Ford. Prior to these cabinet-level positions, he retired as a general from the United States Army, having been Supreme Allied Commander Europe after serving as the vice chief of staff of the Army.

Margaret Mary Heckler was an American Republican Party politician who represented Massachusetts in the United States House of Representatives from 1967 to 1983 and served as Secretary of Health and Human Services and Ambassador to Ireland under President Ronald Reagan.

John Stewart Herrington is an American Republican politician. He served as the United States Secretary of Energy under Ronald Reagan during his second term.
Donald Paul Hodel is an American former politician who served as United States Secretary of Energy, Secretary of the Interior, and chairman of FreeEats.com, which disseminated push polls for the Economic Freedom Fund. He was known during his tenure as Secretary of the Interior for his controversial "Hodel Policy," which stated that disused dirt roads and footpaths could be considered right-of-ways under RS 2477.

Jeane Duane Kirkpatrick was an American diplomat and political scientist who played a major policy role in the foreign policy of the Ronald Reagan administration. An ardent anticommunist, she was a longtime Democrat who became a neoconservative and switched to the Republican Party in 1985. After serving as Ronald Reagan's foreign policy adviser in his 1980 campaign, she became the first woman to serve as United States Ambassador to the United Nations.

Ann McLaughlin Korologos, formerly known as Ann Dore McLaughlin, was the United States Secretary of Labor from 1987 to 1989.

Andrew Lindsay Lewis Jr., generally known as Drew Lewis, was an American businessman and politician from the state of Pennsylvania. He was United States Secretary of Transportation in the first portion of the administration of U.S. President Ronald W. Reagan, and is best known for presiding over the firing of the striking U.S. air traffic controllers in 1981.

Richard Edmund Lyng was a U.S. administrator. A Republican, he served as the Secretary of Agriculture between 1986 and 1989.

Edwin Meese III is an American attorney, law professor, author and member of the Republican Party who served in official capacities within the Ronald Reagan Gubernatorial Administration (1967–1974), the Reagan Presidential Transition Team (1980) and the Reagan White House (1981–1985), eventually rising to hold the position of the 75th United States Attorney General (1985–1988), a position from which he resigned following the Wedtech scandal.

James Clifford "Jim" Miller III is a former U.S. government official and economist who served as chairman of the Federal Trade Commission between 1981 and 1985 and as Budget Director for President Ronald Reagan between 1985 and 1988. He also ran for United States Senate in Virginia, losing the Republican nomination at the convention to Oliver North in 1994 and losing the nomination in the primary to John Warner in 1996.

Samuel Riley Pierce Jr. was Ronald Reagan's Secretary of Housing and Urban Development from January 23, 1981 until January 20, 1989.

Donald Thomas Regan was the 66th United States Secretary of the Treasury from 1981 to 1985 and the White House Chief of Staff from 1985 to 1987 under Ronald Reagan. In the Reagan administration, he advocated "Reaganomics" and tax cuts as a means to create jobs and to stimulate production.

Richard Schultz Schweiker was an American businessman and politician. A member of the Republican Party, he served as the 14th U.S. Secretary of Health and Human Services under President Ronald Reagan from 1981 to 1983. He previously served as a U.S. Representative (1961–1969) and a U.S. Senator (1969–1981) from Pennsylvania. In 1976, Schweiker was Reagan's vice presidential pick during his unsuccessful presidential campaign.

George Pratt Shultz is an American economist, politician, and businessman. He served in various positions under three different Republican presidents and is one of only two people to have held four different Cabinet posts. Shultz played a major role in shaping the foreign policy of the Ronald Reagan administration. From 1974 to 1982, he was an executive of Bechtel Group, an engineering and services company. In the 2010s, Shultz was a prominent figure in the scandal of the biotech firm Theranos, continuing to support it as a board member in the face of mounting evidence of fraud.

William French Smith II was an American lawyer. He was the 74th United States Attorney General.

Richard Lewis Thornburgh is an American lawyer, author and Republican politician who served as the 41st governor of Pennsylvania from 1979 to 1987, and then as the U.S. Attorney General from 1988 to 1991. Before his time as attorney general and governor, he served as the United States Attorney for the Western District of Pennsylvania.

Calvin William Verity Jr. was a U.S. administrator and steel industrialist. He served as the Secretary of Commerce between 1987 and 1989, under President Ronald Reagan.

Vernon A. Walters was a United States Army officer and a diplomat. Most notably, he served from 1972 to 1976 as Deputy Director of Central Intelligence, from 1985 to 1989 as the United States Ambassador to the United Nations and from 1989 to 1991 as Ambassador to the Federal Republic of Germany during the decisive phase of German Reunification. Walters rose to the rank of lieutenant general in the U.S. Army and is a member of the Military Intelligence Hall of Fame.

James Gaius Watt is a public servant who served as U.S. Secretary of the Interior from 1981 to 1983. Often described as "anti-environmentalist", he was one of Ronald Reagan's most controversial cabinet appointments. Watt's pro-development views played an instrumental role in ending the Sagebrush Rebellion.

William Hedgcock Webster is an American attorney and jurist who most recently served as Chair of the Homeland Security Advisory Council from 2005 until 2020. He was a United States District Judge of the United States District Court for the Eastern District of Missouri and a United States Circuit Judge of the United States Court of Appeals for the Eighth Circuit before becoming Director of the Federal Bureau of Investigation (FBI) from 1978 to 1987 and Director of Central Intelligence (CIA) from 1987 to 1991. He is the only person to have held both positions as of September 2020.

Murray Lew Weidenbaum, was an American economist and author. He was the Edward Mallinckrodt Distinguished University Professor and Honorary Chairman of the Murray Weidenbaum Center on the Economy, Government, and Public Policy at Washington University in St. Louis. He has served as Assistant Secretary of the Treasury for Economic Policy (1969–1971). He was chairman of President Ronald Reagan's first Council of Economic Advisors from 1981 to 1982.

Caspar Willard "Cap" Weinberger was an American politician and businessman. As a prominent Republican, he served in a variety of state and federal positions for three decades, including Chairman of the California Republican Party, 1962–68. Most notably he was Secretary of Defense under President Ronald Reagan from 1981 to 1987.

Clayton Keith Yeutter, ONZM served as United States Secretary of Agriculture under President George H. W. Bush from 1989 to 1991 before serving as Counselor to the President in 1992. He served as United States Trade Representative from 1985 to 1989 and as Chairman for the Republican National Committee from 1991 until 1992. Yeutter was employed as a Senior Advisor at the international law firm Hogan Lovells in Washington, D.C.