
Antkind is the 2020 debut novel of American screenwriter and film director Charlie Kaufman.

Axiom's End is a science fiction novel and debut novel by Lindsay Ellis. Set in 2007, the novel is about a U.S. government coverup of contact with extraterrestrial life. Axiom's End entered The New York Times Best Seller list at number 7.

The Cactus League is a 2020 novel by American author and editor Emily Nemens. The novel takes place in Arizona, during spring training. The title refers to the league of Major League Baseball teams that play their spring training games in Arizona. By contrast, other MLB teams, those in the Grapefruit League, play in Florida.

Djinn Patrol on the Purple Line is a novel by Deepa Anappara, published in 2020. Her debut novel, it received wide praise and won the Lucy Cavendish College Fiction Prize in 2019. Djinn Patrol is shortlisted for the 2020 JCB Prize and was longlisted for the 2020 Women's Prize for Fiction.

Escapist Dream is a science fiction novel written by Louis Bulaong and published on July 26, 2020. The novel is set in a near future where virtual reality has become a norm and where geeks can use it to gain superpowers and extraordinary abilities. It was written by the author as a homage to geek culture from comics, films, anime and video games. Upon its release, it garnered positive reception from critics and became one of the best pop culture fiction titles to date.

Florence Adler Swims Forever is the debut novel of American author Rachel Beanland. It was first published in the United States on July 7, 2020 through Simon & Schuster and centers upon a family living in Atlantic City during the 1930s.

Legendborn is a debut young adult fantasy novel by Tracy Deonn. Called "a modern day twist on Arthurian legend" it follows a Black teenage girl who discovers a secret historically white magic society while attending a UNC-Chapel Hill residential pre-college program. The book is the first in the Legendborn series. It was released on September 15, 2020 and published under Simon & Schuster/McElderry. The book was recommended by BuzzFeed, Nerdist, and io9.

Luster is a 2020 debut novel by Raven Leilani. The book follows a Black woman in her twenties who gets involved with a fortysomething white man in an open marriage. Luster was released on August 4, 2020 by Farrar, Straus and Giroux. It received mainly positive critical reception and won the 2020 Kirkus Prize for fiction.

Memoirs and Misinformation is the 2020 debut novel from American-Canadian actor Jim Carrey, with author Dana Vachon, starring a fictionalized version of Carrey. The book has been critically praised.

Memorial is the debut novel by Bryan Washington. It was published by Riverhead Books on October 27, 2020.

Real Life (2020) is the debut novel of Alabama-born American writer Brandon Taylor. Described as a campus novel and a coming-of-age novel, the partly autobiographical book tells of the experiences of a gay, Black doctoral student in a predominantly White, Midwestern PhD program.

Shuggie Bain is the debut novel by Scottish-American writer Douglas Stuart, published in 2020. It tells the story of the youngest of the three children, Shuggie, growing up with his alcoholic mother, Agnes, in the 1980s, in Thatcher-era post-industrial working-class Glasgow, Scotland.

The Unspoken Name is a 2020 fantasy novel, the debut novel by A.K. Larkwood. Csorwe, an orc, is pledged to be sacrificed to the Unspoken God before she is rescued by the wizard Sethennai. She becomes his assassin and spy, dedicating her life to the search for a missing artifact. An unexpected encounter with a young mage calls Csorwe's loyalties into question. The Unspoken Name is the first in the planned Serpent Gates series.