
Heber Hugo Carámbula,, also known under the stage name of Berugo Carámbula, was a Uruguayan actor, comedian and TV host, born in Las Piedras in 1945.

Carlos Enríquez (1898–1971) was an Uruguayan-born actor who worked primarily in Argentina. He starred in the 1950 film Arroz con leche under director Carlos Schlieper.

Santiago Gómez Cousillas was a classic Uruguayan - Argentine actor who appeared in films between 1936 and 1980.

Daniel Hendler is a Uruguayan film, television, and theatre actor who works mainly in the cinema of Argentina, where he lives. He is known for his starring roles in films such as Bottom of the Sea, Family Law, The Paranoids, Phase 7 and award-winning Lost Embrace by director Daniel Burman, with whom he worked many times. Working on both sides of the Río de la Plata, Hendler achieved international recognition due to his awards as an actor. In 2004, he won the Silver Bear for Best Actor at the Berlin Film Festival for his performance in Lost Embrace. He made his debut as screenwriter and director with the film Norberto's Deadline in 2010. Hendler is part of the generation of actors who revitalized the Uruguayan cinema with films like 25 Watts, and is one of the regular actors of the so-called New Argentine Cinema.

Juan Carlos Mareco was a Uruguayan actor and radio and television talk show host. He achieved fame in Spain, Chile and Argentina from the 1960s onwards in comedy roles and as a television host in a variety of genres.

Walter Vidarte was a Uruguayan actor.
Martín Pedro Zabalúa Marramoti, known as Tincho Zabala was a Uruguayan film actor.