Roberto Aguire is an actor and producer. His first major film role was in the 2012 film Struck by Lightning, in which he played the character of Emillio. In 2014, he starred opposite Robin Williams as a troubled young street hustler named Leo in the film Boulevard.

Pasquale Aleardi is a Swiss actor. He is known for playing the role of 'J.D. Salinas' in Resident Evil. He also starred as Billy Flynn in the Broadway production of Chicago.

Lukas Ammann was a Swiss actor who appeared mainly in German and Swiss films and television shows. He continued to work steadily for over 60 years. He is best known for his title role in the German television series Graf Yoster.

Grégoire Aslan was an Armenian actor and musician based in Switzerland.

Antoine Basler is a Swiss actor. He appeared in more than sixty films since 1983.

Joel Basman is a Swiss-Israeli actor.

David Bennent is a Swiss actor.

Rudolf Bernhard or Rudolf Bernhard Conrath was a Swiss comedian, radio personality, and stage and film actor starring usually in Swiss German language cinema and television and stage productions. In 1941 Berhard founded the Bernhard-Theater Zürich.

Jean-Luc Bideau is a Swiss film actor.

Paul Bühlmann was a Swiss comedian, radio personality, and stage and film actor starring usually in Swiss German language cinema and television and stage productions.

Jake Canuso is an Italian-British actor and dancer, who is known for his role in the ITV comedy series Benidorm, in which he played the Solana barman Mateo Castellanos from 2007 until 2018.

Ivan Desny, born Ivan Nikolaevich Desnitskij was a Swiss actor of Russian descent, born in China.

Pierre Dudan (1916–1984) was a Russian-born Swiss actor and singer. He was born in Moscow to a Russian mother and a Swiss father. He married four times.

Bernhard Paul "Buddy" Elias was a Swiss actor and president of the Anne Frank Fonds, the foundation dedicated to preserving the memory of his cousin Anne Frank.

Mirko Ellis was a Swiss-Italian film, stage and television actor.

Inigo Gallo was a Swiss comedian, radio personality, and stage and film actor starring usually in Swiss German language cinema and television and stage productions.

Bruno Ganz was a Swiss actor whose career in German stage, television and film productions spanned nearly 60 years. He was known for his collaborations with the directors Werner Herzog, Éric Rohmer, Francis Ford Coppola, and Wim Wenders, earning widespread recognition with his roles as Jonathan Zimmerman in The American Friend (1977), Jonathan Harker in Nosferatu the Vampyre (1979) and Damiel the Angel in Wings of Desire (1987).

Mickey Hardt is an actor, model and martial artist born in Switzerland. He is best known for his role in the German television series Der Puma - Kämpfer mit Herz. Hardt is skilled in Taekwondo and Savate.
Max Hubacher is a Swiss actor. He became popular due to his acting in The Captain. He has appeared in more than ten films since 2010.

Paul Hubschmid was a Swiss actor. He was most notable for his role as Henry Higgins in a production of My Fair Lady. In some of his Hollywood films he used the name Paul Christian. He appeared in dozens of films and television series between 1938 and 1991. Many of these were German and International productions.

Thomas Jouannet is Swiss actor.

César Keiser or Hanspeter Keiser was a Swiss cabarettist, comedian, radio personality, and stage and film actor usually starring in Swiss German language cinema, television and stage productions.

Michael Koch is a Swiss film director and actor.

Christian Kohlund is a Swiss actor and director.

Dani Levy is a Swiss filmmaker, theatrical director, screenwriter and actor.

Max Loong is a Swiss actor, host and producer of Chinese (Malaysian) descent.

Walo Lüönd was a Swiss movie actor, best known for his role in the movie The Swissmakers along with comedian Emil Steinberger. He has had roles in 102 films and television shows.

Fernand Melgar is a Swiss actor, producer, director and film editor. The son of Spanish immigrants, Melgar has lived in Lausanne since 1963. Melgar's documentary The Fortress garnered eleven international film festival awards.

Hans Heinz Moser was a Swiss television and film actor.

Kacey Mottet Klein is a Swiss actor.

Paul Konrad Muller is a Swiss actor who has appeared mostly in Italian films. His motion picture acting career in Europe spanned a period of 51 years.

Vincent Perez is a Swiss actor, director and photographer. He is best known internationally for playing the title character, Ashe Corven, in The Crow: City of Angels, and for starring in Queen of the Damned, playing Marius de Romanus. Some of his notable films in French cinema include Cyrano de Bergerac, Le Bossu, La Reine Margot and Indochine.

Alfred Rasser was a Swiss comedian, radio personality, and stage and film actor who starred predominantly in Swiss German-language cinema and television and stage productions, but he was also known for the role of Theophil Läppli, a parody on the Swiss militarism.

Walter Roderer was a Swiss actor and screenwriter. He played several leading film roles including the 1959 comedy The Model Husband.

Maximilian Schell was an Austrian-born Swiss film and stage actor, who also wrote, directed and produced some of his own films. He won the Academy Award for Best Actor for the 1961 American film Judgment at Nuremberg, his second acting role in Hollywood. Born in Austria, his parents were involved in the arts and he grew up surrounded by acting and literature. While he was a child, his family fled to Switzerland in 1938 when Austria was annexed by Nazi Germany, and they settled in Zurich. After World War II ended, Schell took up acting or directing full-time. He appeared in numerous German films, often anti-war, before moving on to Hollywood.

Martin Schenkel was a Swiss television actor and musician starring usually in Swiss German television productions.

Jörg Schneider was a Swiss stage and film actor starring usually in Swiss German-language cinema and television and stage productions. He gained great renownedness in the German-speaking area by numerous Kasperle, Pumuckl and fairytale-radio plays records and also adapted plays for the Swiss German language.

François Simon was a Swiss stage and film actor. He appeared in 35 films between 1936 and 1982. He was the son of actor Michel Simon.

Michel Simon was a Swiss actor. He appeared in the notable films La Chienne (1931), Boudu Saved from Drowning (1932), L'Atalante (1934), Port of Shadows (1938), The Head (1959), and The Train (1964). The actor François Simon is his son.

Dominik Tiefenthaler is an Austrian-German actor, mainly working in American TV and films. His work includes Gossip Girl, The Good Wife, Person of Interest, Blue Bloods, The Blacklist, Boardwalk Empire, and the dramatic films Maybe Tomorrow and An Act of War. He has also done voice-over projects, including Grand Theft Auto IV and Wolfenstein: The New Order.

Oliver Tobias Freitag, known professionally as Oliver Tobias, is a Swiss-born UK-based film, stage, and television actor and director.

Bruno Todeschini is a Franco-Swiss actor.

Vico Torriani was a Swiss actor and Schlager singer.

Robert Trösch was a Swiss actor.

Gilles Tschudi is a Swiss actor. He is notable for his 2004 Swiss Film Prize for "Performance in a Supporting Role" as "Secretary Goltz" in Jagged Harmonies - Bach vs. Frederick II and for appearing in theatrical films Grounding (2006), Cargo (2009), and Clouds of Sils Maria (2014). For television he appeared in Lüthi und Blanc (1999–2006), Das Paar im Kahn (2004), Hunkeler macht Sachen (2008), and Hunkeler und die Augen des Ödipus (2012)
Ruedi Walter or Rudolf Walter, was a Swiss comedian, radio personality, and stage and film actor starring usually in Swiss German language cinema and television and stage productions.