WThe Fountain of Youth is a painting by Lucas Cranach the Elder from the year 1546.
WMadonna and Child with Saints is a c.1545-1546 oil on canvas painting by Tintoretto, now in the musée des Beaux-Arts de Lyon.
WThalia is a c.1546 painting by Michele Pannonio, signed by the artist and produced for the 'studiolo' in Belfiore, begun by Lionello d'Este in 1447 and completed by his brother Borso in 1463. After the palace's destruction by fire in 1632 its paintings were dispersed - Thalia is now in the Museum of Fine Arts in Budapest.
WPope Paul III and His Grandsons is a painting in oil on canvas by Titian, housed in the Museo di Capodimonte, Naples. It was commissioned by the Farnese family and painted during Titian's visit to Rome between autumn 1545 and June 1546. It depicts the scabrous relationship between Pope Paul III and his grandsons, Ottavio and Alessandro Farnese. Ottavio is shown in the act of kneeling, to his left; Alessandro, wearing a cardinal's dress, stands behind him to his right. The painting explores the effects of ageing and the manoeuvring behind succession; Paul was at the time in his late seventies and ruling in an uncertain political climate as Charles V, Holy Roman Emperor came into ascendancy.
WPortrait of Pier Luigi Farnese is a heavily-damaged 1546 oil on canvas painting of Pier Luigi Farnese, Duke of Parma by Titian, now in Room 2 of the National Museum of Capodimonte.
WPortrait of Stefano IV Colonna is a painting completed by the Italian Renaissance painter Bronzino and housed in the Pinacoteca of the Gallerie Nazionali di Arte Antica in Rome, Italy.
WThe San Giacomo dell'Orio Altarpiece (or Madonna and Four Saints) is a painting by the Italian High Renaissance artist Lorenzo Lotto, dating from 1546 and housed in the church of San Giacomo dell'Orio in Venice. It is signed and dated on the cartouche hanging at the throne's base, reading "In tempo de Maistro Defendi de Federigo et compagni 1546 Lor. Lot". The canvas is one of the last works executed by Lotto in Venice, before moving to the Marche.
WThe Sarteano Annunciation is a c.1546 oil on canvas painting by Domenico Beccafumi in the church of San Martino in Foro in Sarteano.
WTriptych of Nava and Grimon is a Flemish painting, dated 1546. The central panel is attributed to Pieter Coecke, the lateral panels attributed to his workshop. This triptych is now in the Museo Municipal de Bellas Artes de Santa Cruz de Tenerife, located in the city of the same name in the Canary Islands (Spain).