
Aliasworlds Entertainment is a casual game developer based in Minsk, Belarus. The company was founded in 2001 and released its first game, Gold Sprinter, in 2002.

Ankama is a French entertainment company headquartered in Roubaix, France, focused on the design of massive multiplayer online role playing games. The company is also active in publishing, animation and Web development. It was founded by Anthony Roux, Camille Chafer and Emmanuel Darras. The company name comes from their own names : ANthony, KAmille, MAnu.

Bethesda Game Studios is an American video game developer and a studio of ZeniMax Media based in Rockville, Maryland. The company was established in 2001 as the spin-off of Bethesda Softworks' development unit, with Bethesda Softworks itself retaining a publishing function. The studio is led by Todd Howard as executive producer and Ashley Cheng as studio director. Bethesda Game Studios operates three satellite studios, one in Montreal and two in Texas, and employs 400 people as of July 2018.

Big Ant Studios Pty Ltd is an Australian video game developer founded by chief executive officer Ross Symons in 2001. The studio focus on niche sporting titles, including video game recreations of Cricket, Rugby League, Lacrosse and Tennis. Some of the developer's notable titles include the first AFL Live, as well as the Don Bradman Cricket series and Ashes Cricket franchises, which includes Ashes Cricket and Cricket 19.

Bigbig Studios was a British video game developer based in Leamington Spa, England. It was founded in 2001 by a core team of four former Codemasters employees. The company was set up with the help of parent company Evolution Studios.

Buzz Monkey Software is an American video game developer based in Eugene, Oregon. Buzz Monkey was formed in late 2001 by four former Dynamix employees: senior producer Randy Thompson, senior engineers Jon Milnes and Steve Cordon, and lead artist Barry Drew.

Creative Assembly Sofia is a Bulgarian video game developer based in Sofia. It was founded in May 2001 by Vesselin Handjiev. In July 2008, the company was acquired by Crytek, which then sold it to Creative Assembly in March 2017.

Deck13 Interactive GmbH is a German video game developer and publisher based in Frankfurt. The company was founded in July 2001 by the team behind Artex Software, a studio that primarily developed video games for RISC OS, such as Ankh: The Tales of Mystery. Originally bearing the name TriggerLab, the company was renamed to Deck13 after the release of its first game, Stealth Combat, in 2002. Deck13 is best known for developing the action role-playing games Lords of the Fallen and The Surge. Deck13 also operates a Hamburg-based subsidiary studio, Deck13 Hamburg.

Destination Software Inc., better known as DSI Games, was an American video game publisher and video game developer. Based in Moorestown, New Jersey, DSI is best known for publishing SNOOD. DSI published titles for the Nintendo DS, Wii, Game Boy Advance and PlayStation 2.

Destineer, Inc. was an American umbrella company covering a holding company, a video game publisher, and a video game developer that was based in Minnetonka, Minnesota. The company was founded by Peter Tamte, former executive vice-president of Bungie, in 2001. It developed some original titles and also ported games from Windows to Macs under a number of different brands, including MacSoft and Bold Games.

Digital Eel is a self-funded independent video game development team located in the Seattle, Washington area. Digital Eel is best known for its Infinite Space series of space roguelikes.

Frozenbyte Inc. is a Finnish video game developer founded in 2001 and based in Helsinki, Finland. As of December 2020 it had approximately 130 employees. Frozenbyte's first commercial game was Shadowgrounds for Microsoft Windows. Both Shadowgrounds and its follow-up Shadowgrounds: Survivor were released for Linux in 2009, ported by IGIOS and published by Linux Game Publishing.

Gamepot, Inc., was one of Japan's leading game publishers of massively multiplayer online games and mobile games.

Glu Mobile, Inc. is an American developer and publisher of video games for mobile phones and tablet computers. Founded in San Francisco, California, in 2004, Glu offers products to multiple platforms including Java ME-based devices, Android, Windows Phone, Google Chrome, and Amazon.

Groove Games was a Canadian developer and publisher of video game. Established in 2001, Groove Games had published more than 20 retail game titles on the PC, Xbox, and PlayStation 2 platforms.

High Moon Studios is an American video game developer that used to be a part of Sierra Entertainment. After a period as an independent studio, the developer was acquired by Vivendi Games in January 2006 and retained the current name. It is now owned by Activision Blizzard, a parent company of Activision. It has developed multiple Transformers video games as well as assisting in the development of both Call of Duty: Advanced Warfare and Destiny.

Illusion is a company from Yokohama, Japan famous for developing eroge with 3D graphics. Originally, its games were not allowed to be sold or used outside Japan, and official support was only given in Japanese and for use in Japan. However, with the release of Honey Select Unlimited in coordination with the online English erotic game storefront FAKKU, Illusion's policy has since changed. Prior to this change in policy, they were often translated and released in English and other languages by fans.

Introversion Software Limited is a British video game developer based in Walton-on-Thames, England.

Lodestone Games was a game development studio based in Charlottesville, Virginia. The majority of its employees came from EA/Kesmai after Electronic Arts closed that studio in the fall of 2001. Lodestone Games specialised in the development of both online PC games and client/server technology for online PC games.

Mercury Steam Entertainment S.L., doing business as MercurySteam, is a Spanish video game developer based in San Sebastián de los Reyes, Madrid, Spain. The company makes titles for the major platforms, including PC, Xbox 360 and PlayStation 3. The company was founded by former members of Rebel Act Studios, who previously developed Severance: Blade of Darkness in 2001. Dave Cox is a producer at Konami who has helped out MercurySteam during the Castlevania: Lords of Shadow trilogy.
Monkeystone Games was a video game developer and publisher founded by John Romero, Tom Hall, Stevie Case, and Brian Moon. After its inception in July 2001, Monkeystone published several titles on multiple platforms.

Motion Twin is an independent studio specializing in online video games. Founded in 2001, the company is a worker cooperative enterprise based in Bordeaux, France.

MumboJumbo, LLC is an independent developer of games for personal computers, game consoles and mobile devices. MumboJumbo Mobile, LLC publishes entertainment software for Android and iOS devices.

NaturalMotion is a British video game development company with development offices in London and Brighton and a business office in San Francisco. Founded in November 2001 as a spin-out company from Oxford University, NaturalMotion specialises in creating animation technology for the game and film industries. In January 2014, NaturalMotion was acquired by Zynga for US$527 million.

Q-Games, Limited is a video game developer based in Nakagyō-ku, Kyoto, Japan which works closely with both Nintendo and Sony.

Raw Thrills, Inc. is an arcade game entertainment company based in Skokie, Illinois. It is best known for developing arcade games based on films.

Saber Interactive Incorporated is an American video game developer founded in 2001 with headquarters in Fort Lauderdale, Florida. The company has regional offices in Saint Petersburg, Russia; Madrid, Spain; Minsk, Belarus; Porto, Portugal; Turin, Italy; Denver, Colorado; Sliema, Malta; Kyiv, Ukraine; Sundsvall, Sweden; Sofia, Bulgaria; Budapest, Hungary; Buenos Aires, Argentina; Novi Sad, Vojvodina, Serbia; Calgary, Canada and Montreal, Canada, and employs over 1350 people. Saber was acquired by Embracer Group in February 2020, making the studio a direct subsidiary. The company's portfolio includes World War Z, NBA Playgrounds, SnowRunner, Crysis Remastered and WWE 2K Battlegrounds among others.

San Diego Studio is an American video game developer based in Sorrento Valley, San Diego. A first-party studio for Sony Interactive Entertainment, it is responsible for MLB The Show games. The studio also developed the NBA series, The Mark of Kri, Pain, High Velocity Bowling, and Sports Champions.

Santa Cruz Games was an independent video game developer founded in 2001 in Santa Cruz, California, USA.

SNK Corporation is a Japanese video game hardware and software company. It is the successor to the company Shin Nihon Kikaku and presently owns the SNK video game brand and the Neo Geo video game platform. SNK's predecessor Shin Nihon Kikaku was founded in 1978 by Eikichi Kawasaki. The corporation was initially named Shin Nihon Kikaku . The name was then informally shortened to SNK Corporation in 1981 before becoming the company's official name in 1986.

Spil Games is a Dutch video game developer based in Hilversum. The company publishes free-to-play games for Android and iOS devices, as well as for the Facebook Platform.

Splash Damage Ltd. is a British video game developer that specializes in multiplayer first-person shooter video games. The studio is best known as the creator of the Wolfenstein: Enemy Territory and Enemy Territory: Quake Wars.

Team6 Game Studios B.V. is a Dutch privately owned video game developer based in Assen. It was founded in 2001, but it initially developed several games under a different company name. In 2003 the founders decided to change it to the current title. The company currently employs approximately 40 individuals and is headed by director Ronnie Nelis.

Three Rings Design, Inc. was an online game developer that was founded on March 30, 2001 by Daniel James and Michael Bayne. The company was named in honor of the Three Rings of the Elven-kings in Tolkien mythology.

Tilted Mill Entertainment is a video game developer located in Framingham, Massachusetts. It was founded in 2001 by former Impressions Games lead designer and general manager Chris Beatrice, business manager Peter Haffenreffer, and designer Jeff Fiske. The studio is known for its city-building games.

Turn 10 Studios is an American video game developer based in Redmond, Washington. The company was established in 2001 under Microsoft Game Studios to develop the Forza series for Xbox platforms. The most recent game developed solely by Turn 10 is Forza Motorsport 7, released in 2017.

Unknown Worlds Entertainment is an American video game developer based in San Francisco. The studio is best known for the Natural Selection series and Subnautica.

Wahoo Studios is a computer and video game development company based in Orem, Utah. Founded in 2001, the company largely serves as consultants or on a contract basis working with larger gaming companies such as Electronic Arts and Microsoft. Historically, the development house has mostly been responsible for console games. When developing original titles using internal capital, Wahoo Studios is recognized as NinjaBee. Since the release of the Xbox 360, the developer has supported Xbox Live Arcade with multiple releases, including A Kingdom for Keflings and A World of Keflings.

Wicked Witch Software is a video games developer founded in 2001 by managing director Daniel Visser. Originally operating out of Visser's residence working on Game Boy titles, Wicked Witch moved to a small office. Wicked Witch has grown to be one of Australia's best known studios and is currently located in offices in Eastern Melbourne, Australia. The company has worked with many local and international developers and publishers. The senior staff are industry veterans, some who previously worked at Melbourne House and Torus Games. Wicked Witch has released around 50 titles for PC, handheld and mobile platforms and worked on dozens of other projects across most major consoles including Xbox 360, PlayStation 2 and Wii. Wicked Witch also owns a range of original products and game designs for many platforms, including one of the first MMORPG on the Java ME mobile platform.

XGen Studios, Inc is an independent video game development studio based in Edmonton, Alberta, Canada.