WThe Bardi Altarpiece, is an Italian Mannerist painting by the Italian painter Parmigianino, dating from c. 1521 and housed in the church of Santa Maria at Bardi, Emilia-Romagna, Italy.
WCherub Playing a Lute or Musical Cherub is a 1521 oil on panel painting by Rosso Fiorentino, now in the Uffizi in Florence. It is signed "Rubeus Florentinus" and dated - though the date is unclear it probably reads 1521.
WChrist Taking Leave of his Mother is an oil on canvas painting by Lorenzo Lotto, dated to 1521 and now in the Gemäldegalerie, Berlin. It has several similarities with the small Christ Taking Leave of his Mother by Correggio now in London.
WThe Deposition from the Cross is an altarpiece, completed in 1521, depicting the Deposition of Christ by the Italian Renaissance painter Rosso Fiorentino. It is broadly considered to be the artist's masterpiece. Painted in oil on wood, the painting was previously located in the Duomo of Volterra, but has been moved to the town art gallery.
WHead of a Walrus is a 1521 pen drawing painted in watercolour by the German artist Albrecht Dürer, now in the British Museum, London. At the time the walrus' main European population was around Scandinavia, and they were exotic to inland Europeans. The work reflects Dürer fascination with what he perceived as unusual animals, with similarly intentioned works including depictions of lions and rhinoceros. The drawing created as part of a larger series of 167 drawings of quadrupeds.
WHead of Christ is a painting in oil on panel by the Italian Renaissance painter Correggio, dated 1521. It depicts the head of Christ, wearing the crown of thorns. In the background there is a white cloth showing that the image represents the Veil of Veronica, but Christ's head is given volume through alternate use of light and dark shadows. The painting is in the J. Paul Getty Museum in Malibu, Los Angeles. Correggio was known for creating some of the most sumptuous religious paintings of the period. The Getty Museum considers this artwork as one of the masterpieces of painting held by the museum.
WThe Holy Cross Standard is a 1520-1521 oil on canvas painting by Moretto da Brescia, commissioned by the Brescia's city council for the Company of the Guardians of the Holy Cross, guardians of the Sante Croci treasury at the city's Old Cathedral. It is now in the Pinacoteca Tosio Martinengo in the city.
WHoly Family with the Infant Saint John the Baptist is an unfinished c.1521 oil on panel painting by Rosso Fiorentino, produced early in his stay in Volterra. The Christ Child's pose is influenced by that in Andrea del Sarto's Madonna of the Harpies (1517). The work is now in the Walters Art Museum in Baltimore.
WHoly Trinity is a fresco in San Severo chapel in San Severo church in Perugia, executed by Raphael and Perugino.
WThe Infant Saint John the Baptist is a c.1521 oil on panel painting by Rosso Fiorentino, now in a private collection in Florence. Stylistically close to the artist's Volterra Deposition, its nervy contour lines and gaunt brushstrokes are also similar to his Holy Family with the Infant Saint John the Baptist.
WThe Portrait of Bernhart von Reesen is a portrait painting by German Renaissance master Albrecht Dürer. It depicts a man wearing a beret and holding a piece of paper against a red background. The oil on panel painting is dated 1521 and is in the collection of the Gemäldegalerie Alte Meister of Dresden, Germany.
WThe Portrait of Lucina Brembati is a painting by the Italian High Renaissance painter Lorenzo Lotto, dating to c. 1521/23. It is housed in the Accademia Carrara of Bergamo, northern Italy.
WThe San Bernardino Altarpiece is a 1521 oil on canvas painting by Lorenzo Lotto, named after the chapel on Via Pignolo in Bergamo, for which it was commissioned by the 'Disciplinati', a lay confraternity. It still hangs in its original position. Lotto also worked on the Santo Spirito Altarpiece at around the same time for the church of Santo Spirito in Bergamo.
WThe Santo Spirito Altarpiece is a 1521 oil on panel painting by Lorenzo Lotto, signed and dated "L. Lotus / 1521". The work shows the Madonna and Child with saints Catherine of Alexandria, Augustine of Hippo, Sebastian and Anthony the Great. At the foot of the throne is John the Baptist as a child with the Lamb of God.
WThe Spello Pietà is a fresco of the Pietà by Perugino executed in 1521-1522. It also shows John the Apostle and Mary Magdalene kneeling either side of the Virgin Mary. It is now sited in the left transept of the Chiesa Santa Maria Maggiore in Spello, but its origins are unknown.
WSt. Jerome in His Study is an oil on panel painting by German Renaissance artist Albrecht Dürer, completed March 1521. It is now in the Museu Nacional de Arte Antiga of Lisbon, Portugal.
WVillamagna Altarpiece is a 1521 oil on panel painting by Rosso Fiorentino, produced for Pieve dei Santi Giovanni Battista e Felicita, Villamagna's parish church, where it remained until the mid 1860s. It is now in the Diocesan Museum in Volterra. The artist's second commission in Volterra after Deposition, it is signed and dated in the lower left-hand corner. To the left of the Madonna and Child is John the Baptist in his camel-skin tunic and holding a cross, whilst to the left is Saint Bartholomew holding an open book and the knife used to flay him.