
Cairo is the capital of Egypt and the largest city in the Arab world. Its metropolitan area, with a population of over 20 million, is the largest in Africa, the Arab world, and the Middle East, and the 6th-largest in the world. Cairo is associated with ancient Egypt, as the famous Giza pyramid complex and the ancient city of Memphis are located in its geographical area. Located near the Nile Delta, Cairo was founded in 969 AD by the Fatimid dynasty, but the land composing the present-day city was the site of ancient national capitals whose remnants remain visible in parts of Old Cairo. Cairo has long been a centre of the region's political and cultural life, and is titled "the city of a thousand minarets" for its preponderance of Islamic architecture. Cairo is considered a World City with a "Beta +" classification according to GaWC.

Edfu is an Egyptian city, located on the west bank of the Nile River between Esna and Aswan, with a population of approximately sixty thousand people. Edfu is the site of the Ptolemaic Temple of Horus and an ancient settlement, Tell Edfu. About 5 km (3.1 mi) south of Edfu are remains of ancient pyramids.

El Mahmoudia is an Egyptian city on the connection point between the Nile and Mahmoudiyah canal. It's a city with a history despite its modernity. It was one of the most important trade ports on the Nile River. Trading ships traveling from Upper Egypt and Lower Egypt to Alexandria passed through its lock and up the Mahmoudiyah Canal. Also trading ships from Alexandria carried imported merchandises to Cairo passing by it.
Jinja is a city in the Eastern Region of Uganda, located on the shores of Lake Victoria and lies in the north of the lake.

Juba is the capital and largest city of South Sudan. The city is situated on the White Nile and also serves as the capital of Central Equatoria State. It is the newest capital city with a population of 525,953 in 2017. It has an area of 52 km (32 mi), with the metropolitan area covering 336 km (209 mi).

Karima is a town in Northern State in Sudan some 400 km from Khartoum on a loop of the Nile.

Khartoum or Khartum is the capital of Sudan. With a population of 5,274,321, its metropolitan area is the largest in Sudan. Khartoum is located at the confluence of the White Nile, flowing north from Lake Victoria, and the Blue Nile, flowing west from Lake Tana in Ethiopia. The location where the two Niles meet is known as al-Mogran or al-Muqran. From there, the Nile continues to flow north towards Egypt and the Mediterranean Sea.

Khartoum North or Khartoum Bahri is a city in Khartoum State, lying to the north of Khartoum city, the capital of the Republic of Sudan. It is located on the north bank of the Blue Nile and the east bank of the River Nile, near the confluence of the Blue Nile with the White, and bridges connect it with both Khartoum to its south and Omdurman to its west.

Kimaka is a neighborhood in the city of Jinja, in the Eastern Region of Uganda.

Masindi Port is a town in Uganda.

Melut is a community in the Upper Nile state of South Sudan, headquarters of Melut County.

Mongalla or Mangalla is a community in Central Equatoria State in South Sudan, on the east side of the Bahr al Jebel or White Nile river. It lies about 75 km by road northeast of Juba. The towns of Terekeka and Bor lie downstream, north of Mongalla.

Namasagali is a town in Eastern Uganda. It is one of the metropolitan areas in Kamuli District.

Njeru is a town in Buikwe District, Central Region of Uganda. It is the largest town in the district. It is mainly a residential town. It hosts industries such as Nyanza Textiles Limited(Nytil), a textiles manufacturer, Nile breweries limited, East African packaging limited.
Omdurman is the most populated city in Sudan and Khartoum State, lying on the western banks of the River Nile, opposite the capital, Khartoum.

Pakwach is a town in the Northern Region of Uganda. It is the main commercial, political and administrative center of Pakwach District.

Paraa is a location in Northern Uganda.

Tahta is a city in the Sohag Governorate of Upper Egypt. It is located on the west bank of the Nile. Tahta had a population of 85,528 in the 2017 census. Modern name is believed by Egyptologists to have derived from the word Ta-ho-ty. Two famous monasteries are located near Tahta, the White Monastery and the Red Monastery.

Terekeka is a community in Terekeka State, South Sudan. It is the headquarters of Terekeka County. Terekeka town lies on the western bank of the Nile, 53 miles north of Juba town.