
The 2012 Acrobatic Gymnastics World Championships was the 23rd edition of acrobatic gymnastics competition and were held in Lake Buena Vista, Florida, United States from April 16 to April 18, 2012. It was held at the ESPN Wide World of Sports Complex HP Field House.
The 2012 Boston College Eagles football team represented Boston College in the 2012 NCAA Division I FBS football season. They were led by fourth year head coach Frank Spaziani and played their home games at Alumni Stadium. They were a member of the Atlantic Division of the Atlantic Coast Conference.

The 2012 FCBL All-Star Game was the inaugural exhibition game between all-stars from the Futures Collegiate Baseball League's Original Four teams and the five new 2012 expansion teams. The game was held at Holman Stadium in Nashua, New Hampshire, the home field of the inaugural FCBL Champions' Nashua Silver Knights on July 26, 2012.

The 2012 United States Women's Curling Championship took place from February 11 to 18 at the IceWorks Skating Complex in Aston, Pennsylvania. It was held in conjunction with the 2012 United States Men's Curling Championship. The winning team, skipped by Madison Dew, will represent the United States at the 2012 Ford World Women's Curling Championship in Lethbridge, Alberta. The first and second placed teams, skipped respectively by Madison Dew and Cassandra Potter, earned qualification spots to the 2014 United States Olympic Curling Trials, which will determine the teams that will represent the United States at the 2014 Winter Olympics.

The 2012 Belmont Stakes was the 144th running of the Belmont Stakes and the race was won by Union Rags ridden by jockey John Velazquez. It was broadcast in the United States by NBC. The post time was scheduled for 6:35 p.m. EDT.

The 2012 Boston Marathon took place in Boston, Massachusetts on Monday April 16, 2012. It was the 116th edition of the mass-participation marathon. Organized by the Boston Athletic Association, it was the first of the World Marathon Majors series to be held in 2012. A total of 22,426 runners started the race. The competition was held in hot running conditions, reaching 88 degrees Fahrenheit that afternoon, and some of the 27,000 registered runners opted to take up the organizers' offer to defer their entry until the 2013 race.

The 2012 Chicago Marathon was the 35th edition of the annual marathon race in Chicago, Illinois and was held on Sunday, October 7. An IAAF Gold Label Road Race, it was the fourth and final World Marathon Majors event to be held that year. Tsegaye Kebede won the men's race in a course record of 2:04:38 hours and Atsede Baysa was the women's winner in a personal best of 2:22:03. A total of 37455 runners finished the race.

The Cleveland Squash Classic 2012 is the women's edition of the 2012 Cleveland Classic, which is a tournament of the WSA World Tour event International. The event took place at the Cleveland Racket Club in Cleveland, Ohio in United States from 29 January to 1 February. Nicol David won her first Cleveland Classic trophy, beating Laura Massaro in the final.

The 2012 CONCACAF Men's Olympic Qualifying Tournament was an association football competition to determine the two participants at the 2012 Summer Olympics.

The 2012 Masters Tournament was the 76th Masters Tournament, held April 5–8 at Augusta National Golf Club in Augusta, Georgia. Bubba Watson won the year's first major championship on the second hole of a sudden-death playoff, defeating Louis Oosthuizen. It was his first major title and his fourth victory on the PGA Tour. Watson was the eighth consecutive first-time major champion, and the 14th winner in as many majors. He won a second Masters two years later in 2014.

The North American Open 2012 is the men's edition of the 2012 North American Open, which is a PSA World Series event Gold. The event took place at the Westwood Club in Richmond, Virginia in the United States from 20 to 25 February. James Willstrop won his second North American Open trophy, beating Ramy Ashour in the final.

The Men's J. P. Morgan Tournament of Champions 2012 is the men's edition of the 2012 Tournament of Champions, which is a PSA World Series event Gold. The event took place at the Grand Central Terminal in New York City in the United States from 20 January to 26 January. Nick Matthew won his first Tournament of Champions trophy, beating James Willstrop in the final.

The 2012 NCAA Bowling Championship was the ninth annual tournament to determine the national champion of women's NCAA collegiate ten-pin bowling. The tournament was played at Freeway Lanes in Wickliffe, Ohio from April 13–14, 2012.

The New York City Marathon is an annual marathon that courses through the five boroughs of New York City. It is the largest marathon in the world, with 53,5627 finishers in 2019 and 98,247 applicants for the 2017 race. Along with the Boston Marathon, it is among the pre-eminent long-distance annual running events in the United States and is one of the World Marathon Majors.

The United States competed at the 2012 Summer Paralympics in London, United Kingdom, from August 29 to September 9, 2012.

The 2012 PGA Championship was the 94th PGA Championship, played August 9–12 at the Ocean Course of the Kiawah Island Golf Resort in Kiawah Island, South Carolina, southwest of Charleston. Rory McIlroy shot a bogey-free 66 (−6) in the final round to win his second major title by eight strokes over runner-up David Lynn.

The 2012 Players Championship was a golf tournament in Florida on the PGA Tour, held May 10–13 at TPC Sawgrass in Ponte Vedra Beach, southeast of Jacksonville. It was the 39th Players Championship and was won by Matt Kuchar, two strokes ahead of four runners-up.

The 2012 Preakness Stakes was the 137th running of the Preakness Stakes thoroughbred horse race. The race took place on May 19, 2012, and was televised in the United States on the NBC television network. The post time was 6:20 p.m. EDT. I'll Have Another won the second leg of the Triple Crown, narrowly defeating Bodemeister in a last-furlong push.

The 39th Ryder Cup was held September 28–30, 2012, in the United States at the Medinah Country Club in Medinah, Illinois, a suburb northwest of Chicago. This was the first time that the Ryder Cup was held in Illinois. Europe went into the competition as the cup holders, having won in 2010 to regain it. The team captains were Davis Love III for the U.S. and José María Olazábal for Europe.

The United States of America, represented by the United States Olympic Committee (USOC), competed at the 2012 Summer Olympics in London, from July 27 to August 12, 2012. U.S. athletes have competed at every Summer Olympic Games in the modern era, except the 1980 Summer Olympics in Moscow which they boycotted in protest of the Soviet invasion of Afghanistan. The USOC sent a total of 530 athletes to the Games, 262 men and 268 women, to compete in 25 sports. For the first time in its Olympic history, the United States was represented by more female than male athletes.

The 2012 United States Olympic Trials for track and field were held at Hayward Field in Eugene, Oregon. Organized by USA Track and Field, the ten-day competition lasted from June 21 until July 1 and served as the national championships in track and field for the United States.

The 2012 United States Open Championship was the 112th U.S. Open, played June 14–17 at the Olympic Club in San Francisco, California. Webb Simpson won his first major title, one stroke ahead of runners-up Graeme McDowell and Michael Thompson.

The United States competed at the 2012 Winter Youth Olympics in Innsbruck, Austria.

The 2012 WGC-Accenture Match Play Championship was a golf tournament played February 22–26 at the Ritz-Carlton Golf Club at Dove Mountain in Marana, Arizona, northwest of Tucson. It was the 14th WGC-Accenture Match Play Championship and the first of four World Golf Championships held in 2012.

The 2012 WGC-Bridgestone Invitational was a professional golf tournament held August 2–5 on the South Course of Firestone Country Club in Akron, Ohio. It was the 14th WGC-Bridgestone Invitational tournament, and the third of four World Golf Championships events held in 2012. Keegan Bradley shot a 64 (−6) in the final round to finish with 267 (−13) to win his first WGC event, one stroke ahead of runners-up Jim Furyk and Steve Stricker.

The Women's United States Squash Open 2012 is the women's edition of the 2012 United States Open (squash), which is a WSA World Series event Gold. The event took place at the Daskalakis Athletic Center in Philadelphia, Pennsylvania in the United States from the 7th of October to the 12 October. Nicol David won her first US Open trophy, beating Raneem El Weleily in the final.