
The 2010 Sukma Games, officially known as the 13th Sukma Games, was a Malaysian multi-sport event held in Malacca from 12 to 19 June 2010. Host Malaccan swimmer J. Karthik and Federal Territorian swimmer Chan Kah Yan were announced as Best Sportsman and Best Sportswoman of the event respectively.

The 1st African Youth Games took place in Rabat, Morocco's capital city from 13 to 18 July 2010. The games are targeting young African athletes, both girls and boys of 15–17 years, and about 16 sports codes will be featured at the continental event. athletics, basketball, boxing, fencing, football, gymnastics, Judo, rowing, swimming, Table Tennis, Taekwondo, Tennis, swimming and gymnastics. The Games was organised by the ANOCA as a prelude to the 2010 Summer Youth Olympics, the first olympic youth games to be held in Singapore in August. Tunisia finished leader in the medal table standings.

The 2010 ASEAN University Games officially known as the 15th ASEAN University Games was a Southeast Asian university multi-sport event held in Chiang Mai, Thailand from 15 to 23 December 2010. Around 1064 athletes participated at the event, which featured 183 events in 15 sports.

The 2nd Asian Beach Games were held in Muscat, Oman from 8 December 2010 to 16 December 2010. The opening ceremony was held in the Al-Musannah Sports City, Muscat.

The 2010 Asian Games, also known as the XVI Asian Games, was a multi-sport event celebrated in Guangzhou, Guangdong, China from 12 to 27 November 2010, although several events had commenced from 7 November 2010. This was the second time China had hosted the Games, in which Guangzhou was the second Chinese city to host, after Beijing in 1990. A total of 9,704 athletes from 45 National Olympic Committees (NOCs) competed in 476 events from 42 sports and disciplines, making it the largest event in the history of the Games. Due to reductions in the number of sports to be contested for the 2014 Asian Games, these Games marked the final time that six non-Olympic events would be held during the Asian Games.

The 2010 Asian Para Games, also known as the First Asian Para Games, was a parallel sport event for Asian athletes with a disability held in Guangzhou, China. Two weeks after the conclusion of the 16th Asian Games, It opened on December 12 and closed on December 19, 2010.

The 21st Central American and Caribbean Games took place in Mayagüez, Puerto Rico, from 18 July 2010 to 1 August 2010.

The IX Central American Games was a multi-sport event that took place between 9 and 19 April 2010. The competition featured 23 sports which were contested at various venues, with Panama acting as the primary host country and El Salvador playing a supporting role.

The 2010 Commonwealth Games, officially known as the XIX Commonwealth Games and commonly known as Delhi 2010, was an international multi-sport event that was held in Delhi, India, from 3 to 14 October 2010. A total of 4352 athletes from 71 Commonwealth nations and dependencies competed in 21 sports and 272 events, making it the largest Commonwealth Games to date. It was also the largest international multi-sport event to be staged in Delhi and India, eclipsing the Asian Games in 1951 and 1982. The opening and closing ceremonies were held at the Jawaharlal Nehru Stadium, the main stadium of the event.

The 2010 Gay Games were an international multi-sport event and cultural gathering organized by, and specifically for lesbian, gay, bisexual, and transgender (LGBT) athletes, artists and musicians. It was held from July 31 to August 7, 2010 in Cologne, Germany.

The 2nd Islamic Solidarity Games were going to be an international sporting event scheduled to be held in Iran on 9–25 April 2010. The Games were cancelled following a dispute between the host country and Saudi Arabia.

The 7th Micronesian Games was held August 1–10 in Palau.

NCAA Season 85 is the 2009–2010 season of the National Collegiate Athletic Association of the Philippines. The host for this year will be San Beda College (SBC).

NCAA Season 86 is the 2010–2011 season of the National Collegiate Athletic Association of the Philippines. The host for this year will be San Sebastian College–Recoletos (SSC–R).

The IX South American Games was a multi-sport event held between 19–30 March 2010 in Medellín, Colombia. The Games were organized by the South American Sports Organization (ODESUR), who awarded the Games to the city with 8 votes over the bid by previous host Santiago, Chile.

The 2010 South Asian Games, officially the XI South Asian Games, was a major multi-sport event that took place from 29 January to 8 February 2010 in Dhaka, Bangladesh. This was the third time that the Bangladeshi capital hosted the South Asian Games, thus becoming the first city to hold the games three times.

UAAP Season 73 is the 2010–2011 athletic year of the University Athletic Association of the Philippines. It was hosted by De La Salle University. The men's basketball and the women's volleyball tournaments were aired by ABS-CBN Channel 2 and Studio 23 for the eleventh consecutive year following the renewal of the contract for the broadcast of the games. The opening ceremonies were held on July 10, 2010 with the opening game pitting the season host and the UP Fighting Maroons.

The 2010 Winter Olympics, officially known as the XXI Olympic Winter Games and commonly known as Vancouver 2010, was an international winter multi-sport event held from February 12 to 28, 2010 in Vancouver, British Columbia, Canada, with some events held in the surrounding suburbs of Richmond, West Vancouver and the University Endowment Lands, and in the nearby resort town of Whistler.

The 2010 Winter Paralympics, officially the X Paralympic Winter Games, or the tenth Winter Paralympics, were held in Vancouver and Whistler, Canada from March 12 to 21, 2010. The Opening Ceremony took place in BC Place Stadium in Vancouver and the Closing Ceremony in Whistler. With a theme of "One Inspires Many," the Opening Ceremony featured over 5000 local performers. Fifteen-year-old snowboarder Zach Beaumont, who is an amputee, was the final torch bearer and lit the Games Cauldron. The 2 hours live ceremony was produced by Vancouver-based Patrick Roberge Productions Inc.

The 17th World Festival of Youth and Students (WFYS) was an event that was opened on December 13, 2010 in the South African capital of Pretoria and was organized by the World Federation of Democratic Youth (WFDY). The festival attracted 15,000 people from close to 130 countries and was held under the slogan, "Let's Defeat Imperialism, for a World of Peace, Solidarity and Social Transformation!". It was the second time that an edition of the WFYS has been held in Africa, with the other being in Algeria in 2001

The 2010 Summer Youth Olympics, officially known as the I Summer Youth Olympic Games, was the inaugural edition of the Youth Olympic Games (YOG), an Olympic Games–based event for young athletes aged 15 to 18. Held in Singapore from 14 to 26 August 2010, it was the first International Olympic Committee–sanctioned event held in Singapore. The Games featured about 3,600 athletes aged 14–18 from 204 nations, who competed in 201 events in 26 sports. No official medal tables were published, but the most successful nation was China, followed by Russia. Most unique features of the YOG, such as mixed-NOCs teams and the Culture and Education Programme (CEP), made their debut at the 2010 Games.